ASD

GO:0007193 inhibition of adenylate cyclase activity by G-protein signaling pathway (43)

GeneInput weightStandardRank
ADCY2--102
SSTR2--185
APLP1--335
ADCY10.251466
ADORA1--498
NPY2R0.251597
GNAZ--618
OPRK10.251764
GNAL--860
GRIK30.251976
FLNA--1984
NPY1R0.2511012
GNAI3--1340
ADRA2A0.2511556
GNAI1--1613
HTR1A0.2511672
ADCY8--1906
MCHR10.2512005
DRD20.2512071
CHRM50.2512290
ADCY9--2435
DRD30.2512757
S1PR1--2910
OPRD10.2513266
NPR3--3798
ADCY5--4352
ADCY6--4362
CHRM4--4460
P2RY1--4483
ADCY3--4618
GRM4--5804
RXFP2--16360
GNAI2--6384
S1PR3--6584
DRD40.2517058
RGS1--7315
OPRL10.2518293
ADCY4--8354
SSTR50.2519084
PTGDR2--9477
CORT--11364
INSL3--111614
ADCY7--25198

Network

GO:0007193

Network
Enrichment
NameDescriptionExternal IDs
ADCY2adenylate cyclase 2 (brain) Entrez:108  HGNC: 233  HPRD: 00052  Ensembl: ENSG00000078295 
SSTR2somatostatin receptor 2 Entrez:6752  HPRD: 01674  HGNC: 11331 
APLP1amyloid beta (A4) precursor-like protein 1 Entrez:333  HGNC: 597  HPRD: 00102  Ensembl: ENSG00000105290 
ADCY1adenylate cyclase 1 (brain) Entrez:107  HGNC: 232  HPRD: 00053  Ensembl: ENSG00000164742 
ADORA1adenosine A1 receptor Entrez:134  HPRD: 00042  Ensembl: ENSG00000163485  HGNC: 262 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ADCY2adenylate cyclase 2 (brain)
SSTR2somatostatin receptor 2
APLP1amyloid beta (A4) precursor-like protein 1
ADCY1adenylate cyclase 1 (brain)
ADORA1adenosine A1 receptor
Query geneGeneGene descriptionEdge score
ADCY2ADCY2adenylate cyclase 2 (brain)
SSTR2SSTR2somatostatin receptor 2
APLP1APLP1amyloid beta (A4) precursor-like protein 1
ADCY1ADCY1adenylate cyclase 1 (brain)
ADORA1ADORA1adenosine A1 receptor

Troyanskaya Laboratory - Princeton University