ASD

GO:0002686 negative regulation of leukocyte migration (9)

GeneInput weightStandardRank
PLCB1--161
ADORA1--498
SLIT2--582
GREM1--2654
HOXA7--4063
IL33--11000
C5--115436
HMOX1--20520
ADA0.5124175

Network

GO:0002686

Network
Enrichment
NameDescriptionExternal IDs
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
ADORA1adenosine A1 receptor Entrez:134  HPRD: 00042  Ensembl: ENSG00000163485  HGNC: 262 
SLIT2slit homolog 2 (Drosophila) Entrez:9353  Ensembl: ENSG00000145147  HPRD: 04776  HGNC: 11086 
GREM1gremlin 1, DAN family BMP antagonist Entrez:26585  HGNC: 2001  Ensembl: ENSG00000166923  HPRD: 07048 
HOXA7homeobox A7 Entrez:3204  Ensembl: ENSG00000122592  HGNC: 5108  HPRD: 00838 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
ADORA1adenosine A1 receptor
SLIT2slit homolog 2 (Drosophila)
GREM1gremlin 1, DAN family BMP antagonist
HOXA7homeobox A7
Query geneGeneGene descriptionEdge score
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
ADORA1ADORA1adenosine A1 receptor
SLIT2SLIT2slit homolog 2 (Drosophila)
GREM1GREM1gremlin 1, DAN family BMP antagonist
HOXA7HOXA7homeobox A7

Troyanskaya Laboratory - Princeton University