GO:0022408 negative regulation of cell-cell adhesion (16)

GeneInput weightStandardRank
MAP2K10.251474
PIK3R10.2511065
LEF1--1731
TNR--2784
SERPINE2--2896
WNT1--3263
EPB41L5--3311
NF2--14798
ADIPOQ0.2514834
B4GALNT2--5629
ZNF703--6470
FXYD5--7238
PODXL--12778
TGFB10.25114736
CDH1--123441
GTPBP4--24260

Network

GO:0022408

Network
Enrichment
NameDescriptionExternal IDs
MAP2K1mitogen-activated protein kinase kinase 1 Entrez:5604  HGNC: 6840  HPRD: 01469 
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
LEF1lymphoid enhancer-binding factor 1 Entrez:51176  HGNC: 6551  Ensembl: ENSG00000138795  HPRD: 01075 
TNRtenascin R Entrez:7143  HPRD: 03589  HGNC: 11953  Ensembl: ENSG00000116147 
SERPINE2serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 Entrez:5270  Ensembl: ENSG00000135919  HGNC: 8951  HPRD: 01510 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MAP2K1mitogen-activated protein kinase kinase 1
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
LEF1lymphoid enhancer-binding factor 1
TNRtenascin R
SERPINE2serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
Query geneGeneGene descriptionEdge score
MAP2K1MAP2K1mitogen-activated protein kinase kinase 1
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
LEF1LEF1lymphoid enhancer-binding factor 1
TNRTNRtenascin R
SERPINE2SERPINE2serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2