ASD

GO:0035567 non-canonical Wnt receptor signaling pathway (24)

GeneInput weightStandardRank
SFRP1--204
RAC1--1087
WNT2B--1126
FZD4--11666
VANGL2--1957
FZD10--2606
FZD7--2714
WNT5A--2870
WNT1--3263
DVL3--4438
WNT11--4528
WNT3--4799
WNT3A--4844
WNT7A--6375
GRHL3--6732
WNT9B--8495
WNT5B--11732
DVL2--12293
FZD2--13981
DVL1P1--19166
FZD6--19825
DVL1--21155
WNT4--21840
FZD1--22086

Network

GO:0035567

Network
Enrichment
NameDescriptionExternal IDs
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) Entrez:5879  Ensembl: ENSG00000136238  HPRD: 03627  HGNC: 9801 
WNT2Bwingless-type MMTV integration site family, member 2B Entrez:7482  Ensembl: ENSG00000134245  HGNC: 12781  HPRD: 03574 
FZD4frizzled family receptor 4 Entrez:8322  HPRD: 05203  Ensembl: ENSG00000174804  HGNC: 4042 
VANGL2VANGL planar cell polarity protein 2 Entrez:57216  Ensembl: ENSG00000162738  HGNC: 15511  HPRD: 02758 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SFRP1secreted frizzled-related protein 1
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
WNT2Bwingless-type MMTV integration site family, member 2B
FZD4frizzled family receptor 4
VANGL2VANGL planar cell polarity protein 2
Query geneGeneGene descriptionEdge score
SFRP1SFRP1secreted frizzled-related protein 1
RAC1RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
WNT2BWNT2Bwingless-type MMTV integration site family, member 2B
FZD4FZD4frizzled family receptor 4
VANGL2VANGL2VANGL planar cell polarity protein 2

Troyanskaya Laboratory - Princeton University