ASD

GO:0048678 response to axon injury (39)

GeneInput weightStandardRank
NTRK30.2514
MAP1B--300
NREP--435
MAP2K10.251474
PCSK1--604
JUN--647
TSPO0.2511277
ISL1--1441
FGFR3--11648
DRD20.2512071
SOD1--13330
LGALS1--3679
GIP--3965
RTN4RL2--4365
CST3--14680
LYN--5289
MAX--5628
RTN4RL1--6953
ARG2--7159
ARF4--7739
GIPR--9148
VCAN--9202
FGF2--9627
CTNNA1--11705
SOD2--12001
EPO--12314
TNC--13117
ARG1--114097
RXRA0.25115046
CHST3--15797
SHH--115942
APOE0.25121310
ERBB2--121638
AIF1--23052
TXN2--23468
LTC4S--23557
CDK1--24001
UCK2--25582
LAMB2--25761

Network

GO:0048678

Network
Enrichment
NameDescriptionExternal IDs
NTRK3neurotrophic tyrosine kinase, receptor, type 3 Entrez:4916  Ensembl: ENSG00000140538  HPRD: 01870  HGNC: 8033 
MAP1Bmicrotubule-associated protein 1B Entrez:4131  HPRD: 01139  HGNC: 6836  Ensembl: ENSG00000131711 
NREPneuronal regeneration related protein Entrez:9315  HGNC: 16834  HPRD: 09545  Ensembl: ENSG00000134986 
MAP2K1mitogen-activated protein kinase kinase 1 Entrez:5604  HGNC: 6840  HPRD: 01469 
PCSK1proprotein convertase subtilisin/kexin type 1 Entrez:5122  HGNC: 8743  HPRD: 01201  Ensembl: ENSG00000175426 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NTRK3neurotrophic tyrosine kinase, receptor, type 3
MAP1Bmicrotubule-associated protein 1B
NREPneuronal regeneration related protein
MAP2K1mitogen-activated protein kinase kinase 1
PCSK1proprotein convertase subtilisin/kexin type 1
Query geneGeneGene descriptionEdge score
NTRK3NTRK3neurotrophic tyrosine kinase, receptor, type 3
MAP1BMAP1Bmicrotubule-associated protein 1B
NREPNREPneuronal regeneration related protein
MAP2K1MAP2K1mitogen-activated protein kinase kinase 1
PCSK1PCSK1proprotein convertase subtilisin/kexin type 1

Troyanskaya Laboratory - Princeton University