ASD

GO:0071695 anatomical structure maturation (26)

GeneInput weightStandardRank
GRIN1--167
CACNA1A--1231
AKT10.251303
PAX2--459
TGFB2--625
FGFR3--11648
IGF10.2511993
PTGS20.2513176
WNT1--3263
NOTCH1--13360
BMP2--13686
GH1--4570
BARX2--6105
SPINK5--16847
TRPV10.2518765
PPARD--9856
MREG--13121
LEP0.25113368
CDH5--13603
ACVRL1--114027
PSEN1--20241
ERCC2--120724
PSEN2--21431
LYL1--23505
THBS3--24201
MMP2--24926

Network

GO:0071695

Network
Enrichment
NameDescriptionExternal IDs
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1 Entrez:2902  HGNC: 4584  HPRD: 15926  Ensembl: ENSG00000176884 
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit Entrez:773  HPRD: 03004  HGNC: 1388  Ensembl: ENSG00000141837 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
PAX2paired box 2 Entrez:5076  HGNC: 8616  Ensembl: ENSG00000075891  HPRD: 01330 
TGFB2transforming growth factor, beta 2 Entrez:7042  HGNC: 11768  Ensembl: ENSG00000092969  HPRD: 01828 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
AKT1v-akt murine thymoma viral oncogene homolog 1
PAX2paired box 2
TGFB2transforming growth factor, beta 2
Query geneGeneGene descriptionEdge score
GRIN1GRIN1glutamate receptor, ionotropic, N-methyl D-aspartate 1
CACNA1ACACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1
PAX2PAX2paired box 2
TGFB2TGFB2transforming growth factor, beta 2

Troyanskaya Laboratory - Princeton University