ASD

GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway (18)

GeneInput weightStandardRank
ADORA1--498
FBXW7--525
ADRA2A0.2511556
TGFA--1563
ESR10.2511914
FASLG--12766
PDE6H--3301
AGT--13783
ADRA2C--6524
GPER1--7922
ADRA2B--8196
EREG--8504
EGF0.2518839
AFAP1L2--9020
NUP62--19343
ADAM17--11074
EPGN--11496
PDE6G--119831

Network

GO:0045742

Network
Enrichment
NameDescriptionExternal IDs
ADORA1adenosine A1 receptor Entrez:134  HPRD: 00042  Ensembl: ENSG00000163485  HGNC: 262 
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase Entrez:55294  HPRD: 05888  Ensembl: ENSG00000109670  HGNC: 16712 
ADRA2Aadrenoceptor alpha 2A Entrez:150  HGNC: 281  HPRD: 00078  Ensembl: ENSG00000150594 
TGFAtransforming growth factor, alpha Entrez:7039  HPRD: 07522  HGNC: 11765  Ensembl: ENSG00000163235 
ESR1estrogen receptor 1 Entrez:2099  HGNC: 3467  HPRD: 00589  Ensembl: ENSG00000091831 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ADORA1adenosine A1 receptor
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
ADRA2Aadrenoceptor alpha 2A
TGFAtransforming growth factor, alpha
ESR1estrogen receptor 1
Query geneGeneGene descriptionEdge score
ADORA1ADORA1adenosine A1 receptor
FBXW7FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
ADRA2AADRA2Aadrenoceptor alpha 2A
TGFATGFAtransforming growth factor, alpha
ESR1ESR1estrogen receptor 1

Troyanskaya Laboratory - Princeton University