ASD

GO:0055067 monovalent inorganic cation homeostasis (44)

GeneInput weightStandardRank
KCNMA10.25187
SLC12A5--103
KCNA5--1477
KCNJ10--1518
NEDD4L--670
SLC9A6--1007
NOX1--1232
EDNRB--11322
NR3C2--1684
SLC26A4--11842
FASLG--12766
SLC9A2--3340
SLC9A5--3738
AGT--13783
SLC26A9--3949
ATP4A--4829
ATP6V1H--4958
SLC9A7--5098
SLC9A3--5658
ATP6V0A4--6347
ATP6V0E2--7188
SLC9A91.017256
TMPRSS3--17721
MAFG--8454
ATP1A4--9497
ATP6V1B1--9514
EDN1--9566
ATP12A--9584
SLC9A1--9719
AQP11--10019
PPT1--110364
UPK3A--110467
CYP11B2--11354
CLCN3--12049
SLC9A4--12375
CLN3--113525
ATP5B--14819
SLC11A1--19965
RHCG--21645
SLC9A8--22727
GPR89A--22979
CLN6--125203
ATP6V0E1--25295
CLN5--125787

Network

GO:0055067

Network
Enrichment
NameDescriptionExternal IDs
KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1 Entrez:3778  Ensembl: ENSG00000156113  HGNC: 6284  HPRD: 15967 
SLC12A5solute carrier family 12 (potassium/chloride transporter), member 5 Entrez:57468  Ensembl: ENSG00000124140  HGNC: 13818  HPRD: 09469 
KCNA5potassium voltage-gated channel, shaker-related subfamily, member 5 Entrez:3741  Ensembl: ENSG00000130037  HPRD: 08888  HGNC: 6224 
KCNJ10potassium inwardly-rectifying channel, subfamily J, member 10 Entrez:3766  Ensembl: ENSG00000177807  HGNC: 6256  HPRD: 03732 
NEDD4Lneural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase Entrez:23327  HGNC: 7728  HPRD: 05903  Ensembl: ENSG00000049759 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1
SLC12A5solute carrier family 12 (potassium/chloride transporter), member 5
KCNA5potassium voltage-gated channel, shaker-related subfamily, member 5
KCNJ10potassium inwardly-rectifying channel, subfamily J, member 10
NEDD4Lneural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
Query geneGeneGene descriptionEdge score
KCNMA1KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1
SLC12A5SLC12A5solute carrier family 12 (potassium/chloride transporter), member 5
KCNA5KCNA5potassium voltage-gated channel, shaker-related subfamily, member 5
KCNJ10KCNJ10potassium inwardly-rectifying channel, subfamily J, member 10
NEDD4LNEDD4Lneural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase

Troyanskaya Laboratory - Princeton University