ASD

GO:0007195 inhibition of adenylate cyclase activity by dopamine receptor signaling pathway (5)

GeneInput weightStandardRank
FLNA--1984
DRD20.2512071
DRD30.2512757
ADCY5--4352
DRD40.2517058

Network

GO:0007195

Network
Enrichment
NameDescriptionExternal IDs
FLNAfilamin A, alpha Entrez:2316  HPRD: 02060  HGNC: 3754  Ensembl: ENSG00000196924 
DRD2dopamine receptor D2 Entrez:1813  HPRD: 00539  Ensembl: ENSG00000149295  HGNC: 3023 
DRD3dopamine receptor D3 Entrez:1814  HGNC: 3024  Ensembl: ENSG00000151577  HPRD: 00540 
ADCY5adenylate cyclase 5 Entrez:111  Ensembl: ENSG00000173175  HGNC: 236  HPRD: 08973 
DRD4dopamine receptor D4 Entrez:1815  Ensembl: ENSG00000069696  HGNC: 3025  HPRD: 00541 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
FLNAfilamin A, alpha
DRD2dopamine receptor D2
DRD3dopamine receptor D3
ADCY5adenylate cyclase 5
DRD4dopamine receptor D4
Query geneGeneGene descriptionEdge score
FLNAFLNAfilamin A, alpha
DRD2DRD2dopamine receptor D2
DRD3DRD3dopamine receptor D3
ADCY5ADCY5adenylate cyclase 5
DRD4DRD4dopamine receptor D4

Troyanskaya Laboratory - Princeton University