ASD

GO:0048066 developmental pigmentation (33)

GeneInput weightStandardRank
GNAQ--490
OCA2--11199
EDNRB--11322
SOX10--11510
EDN3--11522
ZIC2--11550
CITED1--1867
TYRP1--12121
FOXD3--2272
SLC45A2--12347
GPR143--13103
GNA11--3167
TYR0.2513261
MITF--13985
FOXD1--5256
FOXD2--5493
AP3D1--5872
FOXD4L1--7290
GLI3--19032
FOXD4--9835
FOXD4L4--10472
SOD2--12001
MREG--13121
BLOC1S3--13724
MLPH0.25113952
HPS4--14664
FOXD4L5--16935
FOXD4L2--17995
FOXD4L6--19463
RAB27A--21745
HPS6--22765
BLOC1S6--23642
HPS1--124910

Network

GO:0048066

Network
Enrichment
NameDescriptionExternal IDs
GNAQguanine nucleotide binding protein (G protein), q polypeptide Entrez:2776  HGNC: 4390  HPRD: 02998 
OCA2oculocutaneous albinism II Entrez:4948  Ensembl: ENSG00000104044  HPRD: 01945  HGNC: 8101 
EDNRBendothelin receptor type B Entrez:1910  Ensembl: ENSG00000136160  HPRD: 08834  HGNC: 3180 
SOX10SRY (sex determining region Y)-box 10 Entrez:6663  Ensembl: ENSG00000100146  HGNC: 11190  HPRD: 03752 
EDN3endothelin 3 Entrez:1908  HGNC: 3178  Ensembl: ENSG00000124205  HPRD: 00570 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNAQguanine nucleotide binding protein (G protein), q polypeptide
OCA2oculocutaneous albinism II
EDNRBendothelin receptor type B
SOX10SRY (sex determining region Y)-box 10
EDN3endothelin 3
Query geneGeneGene descriptionEdge score
GNAQGNAQguanine nucleotide binding protein (G protein), q polypeptide
OCA2OCA2oculocutaneous albinism II
EDNRBEDNRBendothelin receptor type B
SOX10SOX10SRY (sex determining region Y)-box 10
EDN3EDN3endothelin 3

Troyanskaya Laboratory - Princeton University