ASD

GO:0030073 insulin secretion (26)

GeneInput weightStandardRank
NEUROD1--1136
RIMS2--273
RAPGEF40.251635
CAMK2G--925
VGF0.2511243
FKBP1B--1700
CPLX1--2921
ACVR2B--13179
MC4R0.2513280
CPLX3--3906
HNF1A--15114
SLC30A8--15810
SMAD2--7224
SLC18A2--7407
ANXA1--7465
CCKAR--7616
PDX1--18378
HNF1B--19562
GAL--9612
FAM3B--9848
GPR119--13231
CYB5R4--14019
MAFA--14795
DGAT1--15809
EIF2AK3--20407
IL1RN0.25124819

Network

GO:0030073

Network
Enrichment
NameDescriptionExternal IDs
NEUROD1neuronal differentiation 1 Entrez:4760  HPRD: 03428  HGNC: 7762  Ensembl: ENSG00000162992 
RIMS2regulating synaptic membrane exocytosis 2 Entrez:9699  HGNC: 17283  HPRD: 09436 
RAPGEF4Rap guanine nucleotide exchange factor (GEF) 4 Entrez:11069  Ensembl: ENSG00000091428  HGNC: 16626  HPRD: 06929 
CAMK2Gcalcium/calmodulin-dependent protein kinase II gamma Entrez:818  HPRD: 03672  Ensembl: ENSG00000148660  HGNC: 1463 
VGFVGF nerve growth factor inducible Entrez:7425  HPRD: 03717  Ensembl: ENSG00000128564  HGNC: 12684 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NEUROD1neuronal differentiation 1
RIMS2regulating synaptic membrane exocytosis 2
RAPGEF4Rap guanine nucleotide exchange factor (GEF) 4
CAMK2Gcalcium/calmodulin-dependent protein kinase II gamma
VGFVGF nerve growth factor inducible
Query geneGeneGene descriptionEdge score
NEUROD1NEUROD1neuronal differentiation 1
RIMS2RIMS2regulating synaptic membrane exocytosis 2
RAPGEF4RAPGEF4Rap guanine nucleotide exchange factor (GEF) 4
CAMK2GCAMK2Gcalcium/calmodulin-dependent protein kinase II gamma
VGFVGFVGF nerve growth factor inducible

Troyanskaya Laboratory - Princeton University