ASD

GO:0032352 positive regulation of hormone metabolic process (12)

GeneInput weightStandardRank
IGF1R--631
HIF1A--1008
POR0.2512359
LHCGR0.2512362
PAX8--13021
CYP17A10.2513171
GATA3--3207
BMP6--3242
KDM1A--15967
WNT4--21840
IGF20.25123391
ARNT--24282

Network

GO:0032352

Network
Enrichment
NameDescriptionExternal IDs
IGF1Rinsulin-like growth factor 1 receptor Entrez:3480  Ensembl: ENSG00000140443  HPRD: 00932  HGNC: 5465 
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Entrez:3091  HGNC: 4910  Ensembl: ENSG00000100644  HPRD: 04517 
PORP450 (cytochrome) oxidoreductase Entrez:5447  HGNC: 9208  Ensembl: ENSG00000127948  HPRD: 00485 
LHCGRluteinizing hormone/choriogonadotropin receptor Entrez:3973  HGNC: 6585  Ensembl: ENSG00000138039  HPRD: 01073 
PAX8paired box 8 Entrez:7849  HPRD: 01335  HGNC: 8622  Ensembl: ENSG00000125618 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
IGF1Rinsulin-like growth factor 1 receptor
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
PORP450 (cytochrome) oxidoreductase
LHCGRluteinizing hormone/choriogonadotropin receptor
PAX8paired box 8
Query geneGeneGene descriptionEdge score
IGF1RIGF1Rinsulin-like growth factor 1 receptor
HIF1AHIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
PORPORP450 (cytochrome) oxidoreductase
LHCGRLHCGRluteinizing hormone/choriogonadotropin receptor
PAX8PAX8paired box 8

Troyanskaya Laboratory - Princeton University