ASD

GO:0080135 regulation of cellular response to stress (181)

GeneInput weightStandardRank
NTRK30.2514
PLCB1--161
GRIK20.51142
MAPK8IP2--275
AKT10.251303
MAPK8IP1--1326
MAP3K9--500
OMG0.251521
COPS5--623
TGFB2--625
MAP4K4--630
RAP2A--652
UBE2N--693
EYA1--1828
MIF0.251948
BMP7--987
CDC42--1083
NDEL10.2511194
UBE2V2--1207
MAP3K5--1245
PPP4C0.2511264
PRKCG--11280
SPAG9--1398
USP1--1616
SEMA4C--1644
SIRT1--1656
MAP3K10--1767
RTN4--1776
NCOR1--1807
GAB1--1864
PKN1--1964
XYLT1--12006
PSMD10--2012
MAP3K7--2169
HIPK2--2306
TERF2IP--2316
MSX1--12365
TAOK20.2512490
MAPK8IP3--2496
MID1--2525
FZD10--2606
FZD7--2714
TNR--2784
WNT5A--2870
AKT2--13025
PTK2B--3191
WNT1--3263
SFRP4--3511
DAB2IP--3635
H2AFX--3754
WNT16--3772
CBS0.2514080
FGF10--14373
MECOM--4397
DVL3--4438
DIXDC1--4469
TAOK3--4471
IL1A--4552
ZEB2--4607
EDA2R--4611
TNFRSF11A--14672
MAP4K5--4887
PDCD4--4897
CD44--5047
DUSP19--5073
LYN--5289
TAOK1--5452
PAK1--5556
MDM2--5588
DUSP3--5845
AXIN2--15927
CEBPG--6059
TWIST1--16128
DUSP10--6196
IL1B--16220
BABAM1--6310
WNT7A--6375
SPP1--6377
PPEF2--6387
MAP3K4--6590
MEN1--16723
MAP3K1--16751
RNF8--6838
NFE2L2--6933
FOXO10.2516970
PMAIP1--7387
WNT7B--7693
TRAF4--7752
TLR6--7973
SMYD2--8088
MAP2K7--8382
SNAI1--8474
EDN1--9566
DAXX--9639
CDKN2A--19650
MAP3K2--10013
IL26--10272
FGF19--10321
GSTP10.25110429
FEM1B--10471
ATM--110590
SCARF1--10690
ITCH--10863
AXIN1--110905
SDCBP--11081
RNF168--11188
HIPK3--11588
FGD4--111677
MDFI--11799
CCL19--11890
BIRC7--12220
PARG--12271
DVL2--12293
UIMC1--12322
TLR9--12436
UBE2V1--12516
FKTN--112941
CLN3--113525
RIPK2--13928
HP--14183
DBNL--14433
MDFIC--14627
TRAF6--14847
AMBP--14902
ZNF675--15034
F2RL1--15088
MTOR--15435
APEX1--15510
FBLN5--115601
TP73--15964
KDM1A--15967
MYD88--17730
EYA3--18000
CCL21--19130
HDAC3--19605
TNF0.25119823
TPD52L1--20081
GPS2--20293
TLR3--20315
PPP4R2--20640
BECN1--20816
MAP4K2--20924
ERCC8--121190
CCR7--21314
TIRAP--21732
CARD9--122070
KLK8--22103
BRE--22289
MAP4K1--22293
MUL1--22450
RPA2--22606
CD74--22633
SETD8--22651
NOD2--122677
CD36--22749
PTPLAD1--22865
SNAI2--122934
CD27--22987
SH3RF1--23055
RIPK1--23173
BRCC3--23262
MAP3K11--23341
TRAF2--23633
NOD1--23711
SYK--23795
FAM175A--23969
EEF1E1--24071
BRCA1--124158
RTEL1--24377
MAP3K6--24401
POLH--124799
IL1RN0.25124819
NBR1--24836
MGMT--25043
AIDA--25079
TMEM161A--25083
FOXM1--25108
ATR--125123
DUSP22--25132
RPS3--25466
IGBP1--25575

Network

GO:0080135

Network
Enrichment
NameDescriptionExternal IDs
NTRK3neurotrophic tyrosine kinase, receptor, type 3 Entrez:4916  Ensembl: ENSG00000140538  HPRD: 01870  HGNC: 8033 
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
GRIK2glutamate receptor, ionotropic, kainate 2 Entrez:2898  Ensembl: ENSG00000164418  HGNC: 4580  HPRD: 00692 
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2 Entrez:23542  HPRD: 09674  Ensembl: ENSG00000008735  HGNC: 6883 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NTRK3neurotrophic tyrosine kinase, receptor, type 3
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
GRIK2glutamate receptor, ionotropic, kainate 2
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2
AKT1v-akt murine thymoma viral oncogene homolog 1
Query geneGeneGene descriptionEdge score
NTRK3NTRK3neurotrophic tyrosine kinase, receptor, type 3
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
GRIK2GRIK2glutamate receptor, ionotropic, kainate 2
MAPK8IP2MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1

Troyanskaya Laboratory - Princeton University