ASD

GO:0032414 positive regulation of ion transmembrane transporter activity (22)

GeneInput weightStandardRank
CALM3--195
CALM1--708
ADRB1--866
ACTN4--11332
TRPC6--11908
CALM2--2360
WNK30.2512993
AGT--13783
NKX2-50.2515490
STIM2--5530
PLCG1--5952
HOMER10.2516115
DRD40.2517058
CXCL12--7204
GLP1R--7291
CCKAR--7616
EFCAB4B--7865
STIM1--15530
ZP3--15811
VDR--20212
ADRB20.25122718
PLCG2--24804

Network

GO:0032414

Network
Enrichment
NameDescriptionExternal IDs
CALM3calmodulin 3 (phosphorylase kinase, delta) Entrez:808  HPRD: 00243  Ensembl: ENSG00000160014  HGNC: 1449 
CALM1calmodulin 1 (phosphorylase kinase, delta) Entrez:801  HPRD: 00241  HGNC: 1442  Ensembl: ENSG00000198668 
ADRB1adrenoceptor beta 1 Entrez:153  HGNC: 285  Ensembl: ENSG00000043591  HPRD: 00181 
ACTN4actinin, alpha 4 Entrez:81  HPRD: 05222  HGNC: 166 
TRPC6transient receptor potential cation channel, subfamily C, member 6 Entrez:7225  Ensembl: ENSG00000137672  HPRD: 04710  HGNC: 12338 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CALM3calmodulin 3 (phosphorylase kinase, delta)
CALM1calmodulin 1 (phosphorylase kinase, delta)
ADRB1adrenoceptor beta 1
ACTN4actinin, alpha 4
TRPC6transient receptor potential cation channel, subfamily C, member 6
Query geneGeneGene descriptionEdge score
CALM3CALM3calmodulin 3 (phosphorylase kinase, delta)
CALM1CALM1calmodulin 1 (phosphorylase kinase, delta)
ADRB1ADRB1adrenoceptor beta 1
ACTN4ACTN4actinin, alpha 4
TRPC6TRPC6transient receptor potential cation channel, subfamily C, member 6

Troyanskaya Laboratory - Princeton University