ASD

GO:0030835 negative regulation of actin filament depolymerization (25)

GeneInput weightStandardRank
SHROOM2--763
CAPZB--953
SPTBN4--1223
DMTN--1226
SPTBN2--11344
ADD2--1685
SPTAN1--12078
SPTB--2288
CAPZA2--2428
CAPZA1--2513
SPTA1--14158
CAPZA3--5405
RDX--15514
SPTBN5--5948
SPTBN1--8272
ADD1--19458
AVIL--10360
CAPG--10638
SCIN--11105
TWF2--21814
GSN--122198
VIL1--22201
VILL--23074
LIMA1--24245
TRIOBP--124727

Network

GO:0030835

Network
Enrichment
NameDescriptionExternal IDs
SHROOM2shroom family member 2 Entrez:357  Ensembl: ENSG00000146950  HGNC: 630  HPRD: 02113 
CAPZBcapping protein (actin filament) muscle Z-line, beta Entrez:832  HGNC: 1491  HPRD: 11872  Ensembl: ENSG00000077549 
SPTBN4spectrin, beta, non-erythrocytic 4 Entrez:57731  HPRD: 09372  HGNC: 14896  Ensembl: ENSG00000160460 
DMTNdematin actin binding protein Entrez:2039  HPRD: 00506  Ensembl: ENSG00000158856  HGNC: 3382 
SPTBN2spectrin, beta, non-erythrocytic 2 Entrez:6712  HGNC: 11276  Ensembl: ENSG00000173898  HPRD: 05404 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SHROOM2shroom family member 2
CAPZBcapping protein (actin filament) muscle Z-line, beta
SPTBN4spectrin, beta, non-erythrocytic 4
DMTNdematin actin binding protein
SPTBN2spectrin, beta, non-erythrocytic 2
Query geneGeneGene descriptionEdge score
SHROOM2SHROOM2shroom family member 2
CAPZBCAPZBcapping protein (actin filament) muscle Z-line, beta
SPTBN4SPTBN4spectrin, beta, non-erythrocytic 4
DMTNDMTNdematin actin binding protein
SPTBN2SPTBN2spectrin, beta, non-erythrocytic 2

Troyanskaya Laboratory - Princeton University