ASD

GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway (34)

GeneInput weightStandardRank
NR3C1--463
PEG10--540
SMAD7--1283
FBN2--1425
ONECUT2--1475
STRAP--1862
SMAD6--2079
LEMD3--12358
NKX2-1--2488
WNT1--3263
SKIL--4016
SKI--4231
ADAMTSL2--4249
SMURF1--4696
CIDEA--5234
TGFB3--15321
BCL9L--5421
PRDM16--5921
FBN1--16138
CHST11--7380
BAMBI--7548
PIN1--8222
TGFBR3--8717
ASPN--10001
DAND5--12393
SKOR2--13004
HSPA5--13639
SKOR1--16408
ENG--117647
EID2--22443
GLG1--22724
TGFB1I1--22730
SNX6--22785
LTBP1--23598

Network

GO:0030512

Network
Enrichment
NameDescriptionExternal IDs
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Entrez:2908  HPRD: 00679  HGNC: 7978  Ensembl: ENSG00000113580 
PEG10paternally expressed 10 Entrez:23089  Ensembl: ENSG00000242265  HGNC: 14005 
SMAD7SMAD family member 7 Entrez:4092  HPRD: 04241  HGNC: 6773  Ensembl: ENSG00000101665 
FBN2fibrillin 2 Entrez:2201  Ensembl: ENSG00000138829  HGNC: 3604  HPRD: 00416 
ONECUT2one cut homeobox 2 Entrez:9480  HGNC: 8139  Ensembl: ENSG00000119547  HPRD: 05354 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PEG10paternally expressed 10
SMAD7SMAD family member 7
FBN2fibrillin 2
ONECUT2one cut homeobox 2
Query geneGeneGene descriptionEdge score
NR3C1NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
PEG10PEG10paternally expressed 10
SMAD7SMAD7SMAD family member 7
FBN2FBN2fibrillin 2
ONECUT2ONECUT2one cut homeobox 2

Troyanskaya Laboratory - Princeton University