ASD

GO:0048259 regulation of receptor-mediated endocytosis (31)

GeneInput weightStandardRank
SYNJ1--178
SH3GL2--301
HNRNPK--746
BICD1--760
RAC1--1087
SGIP1--1331
HIP1--1990
DRD20.2512071
CBL--2611
ANGPT1--3376
SFRP4--3511
PICALM--14018
ARF6--4366
WNT3A--4844
RSPO1--5850
DKK1--6892
PCSK9--8260
MTMR2--18529
VTN--9385
PPT1--110364
SELE--10573
APOC2--11692
CCL19--11890
APOA5--113056
CCL21--19130
APOC3--19472
SERPINE10.25120720
APOC1--21328
PLD2--23098
SCYL2--24230
LDLRAP1--25301

Network

GO:0048259

Network
Enrichment
NameDescriptionExternal IDs
SYNJ1synaptojanin 1 Entrez:8867  Ensembl: ENSG00000159082  HGNC: 11503  HPRD: 09182 
SH3GL2SH3-domain GRB2-like 2 Entrez:6456  HGNC: 10831  Ensembl: ENSG00000107295  HPRD: 05125 
HNRNPKheterogeneous nuclear ribonucleoprotein K Entrez:3190  HGNC: 5044  Ensembl: ENSG00000165119  HPRD: 02834 
BICD1bicaudal D homolog 1 (Drosophila) Entrez:636  Ensembl: ENSG00000151746  HGNC: 1049  HPRD: 03730 
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) Entrez:5879  Ensembl: ENSG00000136238  HPRD: 03627  HGNC: 9801 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SYNJ1synaptojanin 1
SH3GL2SH3-domain GRB2-like 2
HNRNPKheterogeneous nuclear ribonucleoprotein K
BICD1bicaudal D homolog 1 (Drosophila)
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
Query geneGeneGene descriptionEdge score
SYNJ1SYNJ1synaptojanin 1
SH3GL2SH3GL2SH3-domain GRB2-like 2
HNRNPKHNRNPKheterogeneous nuclear ribonucleoprotein K
BICD1BICD1bicaudal D homolog 1 (Drosophila)
RAC1RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)

Troyanskaya Laboratory - Princeton University