ASD

GO:0008624 induction of apoptosis by extracellular signals (119)

GeneInput weightStandardRank
CAMK2B0.25111
KALRN--63
ARHGEF4--203
ABR--211
RASGRF1--213
TRIO--246
CRH--328
TIAM1--369
ARHGEF12--1444
ARHGEF7--492
ADORA1--498
PRKCA--613
ARHGEF9--1639
MCF2--650
YWHAE--772
SST--869
ARHGEF11--870
FGD1--11009
MCF2L--1084
RAC1--1087
MAP3K5--1245
DAPK1--1605
BAD--1647
ITSN1--1679
MAPK8--1764
PREX1--2219
MAPK9--2324
RASGRF2--2464
SOS2--2569
ARHGEF2--2743
FASLG--12766
TIAM2--2771
VAV2--2783
SPECC1L--3048
SOS1--13181
NGFR0.2513554
NGF0.2513749
DEDD--3922
VAV3--4024
ARHGEF3--4334
ARHGEF17--4415
MAGED1--4429
AKAP13--4708
TNFRSF25--4874
NDUFA13--14969
BCL2L11--5454
PTH--5481
UBC--5781
DAP--6553
DAP3--7064
BAX--7313
NET1--7744
NGEF--7891
CASP30.2517989
SENP1--8177
CD3E--8226
ARHGEF18--8718
CASP8AP2--8768
NGFRAP1--8980
FGD3--9083
ADORA2A0.2519605
DAXX--9639
PLEKHG2--10000
FAS--110857
CASP10--111026
FGD4--111677
SSTR3--12043
PLEKHG5--12196
CD5--12584
APH1A--12706
TNFRSF10B--12951
CASP2--12965
ARHGEF6--13050
SORT1--13249
BID--14222
SPN--14301
TRAF6--14847
BAK1--15240
PDCD6--15692
DEDD2--16059
TNFRSF1A--16905
CD380.25117453
FGD2--18783
AATF--19262
RIPK3--19573
TNF0.25119823
VDR--20212
PSEN1--20241
ARHGEF16--20461
DPF2--20498
BTK--120625
FASTK0.25120951
ITGB3BP--21140
PSEN2--21431
TICAM1--21522
ARHGAP4--21597
TNFRSF10A--21606
OBSCN--21654
PSENEN--121944
NCSTN--122027
UBB--22223
IFI27--22562
FADD--22674
CFLAR--22762
APH1B--22814
DIABLO--22913
RPS27A--22920
CASP8--122936
VAV1--23026
RIPK1--23173
SMPD2--23597
TRAF2--23633
UBA52--24116
SQSTM1--124354
CRADD--24372
ECT2--24948
TNFSF10--25067
TRADD--25451
TM2D1--25767

Network

GO:0008624

Network
Enrichment
NameDescriptionExternal IDs
CAMK2Bcalcium/calmodulin-dependent protein kinase II beta Entrez:816  Ensembl: ENSG00000058404  HGNC: 1461  HPRD: 12127 
KALRNkalirin, RhoGEF kinase Entrez:8997  HPRD: 06859  HGNC: 4814  Ensembl: ENSG00000160145 
ARHGEF4Rho guanine nucleotide exchange factor (GEF) 4 Entrez:50649  Ensembl: ENSG00000136002  HGNC: 684  HPRD: 05559 
ABRactive BCR-related Entrez:29  HGNC: 81  HPRD: 02649  Ensembl: ENSG00000159842 
RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1 Entrez:5923  HGNC: 9875  Ensembl: ENSG00000058335 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CAMK2Bcalcium/calmodulin-dependent protein kinase II beta
KALRNkalirin, RhoGEF kinase
ARHGEF4Rho guanine nucleotide exchange factor (GEF) 4
ABRactive BCR-related
RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1
Query geneGeneGene descriptionEdge score
CAMK2BCAMK2Bcalcium/calmodulin-dependent protein kinase II beta
KALRNKALRNkalirin, RhoGEF kinase
ARHGEF4ARHGEF4Rho guanine nucleotide exchange factor (GEF) 4
ABRABRactive BCR-related
RASGRF1RASGRF1Ras protein-specific guanine nucleotide-releasing factor 1

Troyanskaya Laboratory - Princeton University