ASD

GO:0007224 smoothened signaling pathway (33)

GeneInput weightStandardRank
PAX60.251355
NKX2-2--771
WNT10B--1030
HIPK1--1034
PTCH1--11149
MAP3K10--1767
HIPK2--2306
PTCHD11.012601
FOXF1--13053
NKX6-1--3174
DYRK2--3180
CDON--3482
HES5--4001
BMP4--15180
HES10.2515662
GLI2--15731
NDST1--5799
SMO0.2515864
BOC--6380
DISP2--6745
TULP3--8569
GLI3--19032
TGFBR2--19756
HHAT--11622
PTCHD2--11804
TCTN2--12763
IFT88--12821
SHH--115942
IFT52--16550
STK36--22089
IFT172--22164
NSDHL--22683
DISP1--23291

Network

GO:0007224

Network
Enrichment
NameDescriptionExternal IDs
PAX6paired box 6 Entrez:5080  HPRD: 06167  Ensembl: ENSG00000007372  HGNC: 8620 
NKX2-2NK2 homeobox 2 Entrez:4821  Ensembl: ENSG00000125820  HGNC: 7835  HPRD: 05213 
WNT10Bwingless-type MMTV integration site family, member 10B Entrez:7480  Ensembl: ENSG00000169884  HGNC: 12775  HPRD: 03548 
HIPK1homeodomain interacting protein kinase 1 Entrez:204851  HGNC: 19006  Ensembl: ENSG00000163349  HPRD: 06418 
PTCH1patched 1 Entrez:5727  Ensembl: ENSG00000185920  HGNC: 9585  HPRD: 03200 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PAX6paired box 6
NKX2-2NK2 homeobox 2
WNT10Bwingless-type MMTV integration site family, member 10B
HIPK1homeodomain interacting protein kinase 1
PTCH1patched 1
Query geneGeneGene descriptionEdge score
PAX6PAX6paired box 6
NKX2-2NKX2-2NK2 homeobox 2
WNT10BWNT10Bwingless-type MMTV integration site family, member 10B
HIPK1HIPK1homeodomain interacting protein kinase 1
PTCH1PTCH1patched 1

Troyanskaya Laboratory - Princeton University