ASD

GO:0051482 elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger (12)

GeneInput weightStandardRank
CALCA--460
DRD10.251662
DRD20.2512071
AGTR1--12898
S1PR1--2910
LPAR1--2975
EDNRA--13271
RXFP3--5237
EDN1--9566
LPAR3--10488
F2R--12498
TGM2--13660

Network

GO:0051482

Network
Enrichment
NameDescriptionExternal IDs
CALCAcalcitonin-related polypeptide alpha Entrez:796  HGNC: 1437  HPRD: 00238  Ensembl: ENSG00000110680 
DRD1dopamine receptor D1 Entrez:1812  HPRD: 00538  HGNC: 3020  Ensembl: ENSG00000184845 
DRD2dopamine receptor D2 Entrez:1813  HPRD: 00539  Ensembl: ENSG00000149295  HGNC: 3023 
AGTR1angiotensin II receptor, type 1 Entrez:185  HPRD: 00107  Ensembl: ENSG00000144891  HGNC: 336 
S1PR1sphingosine-1-phosphate receptor 1 Entrez:1901  HGNC: 3165  HPRD: 03578  Ensembl: ENSG00000170989 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CALCAcalcitonin-related polypeptide alpha
DRD1dopamine receptor D1
DRD2dopamine receptor D2
AGTR1angiotensin II receptor, type 1
S1PR1sphingosine-1-phosphate receptor 1
Query geneGeneGene descriptionEdge score
CALCACALCAcalcitonin-related polypeptide alpha
DRD1DRD1dopamine receptor D1
DRD2DRD2dopamine receptor D2
AGTR1AGTR1angiotensin II receptor, type 1
S1PR1S1PR1sphingosine-1-phosphate receptor 1

Troyanskaya Laboratory - Princeton University