ASD

GO:0040036 regulation of fibroblast growth factor receptor signaling pathway (20)

GeneInput weightStandardRank
FGFR2--1165
RUNX2--1209
OTX2--11295
SPRY2--1552
DUSP6--1889
HHIP--2403
WNT5A--2870
NPTN--3227
SULF1--3312
NGFR0.2513554
SULF2--5996
CTNNB10.2516229
WNT8A--7061
NOG--17650
SPRY1--10579
FGFBP3--11207
PDGFB--12484
FGFBP1--15273
WNT4--21840
THBS1--21993

Network

GO:0040036

Network
Enrichment
NameDescriptionExternal IDs
FGFR2fibroblast growth factor receptor 2 Entrez:2263  HPRD: 01492  Ensembl: ENSG00000066468  HGNC: 3689 
RUNX2runt-related transcription factor 2 Entrez:860  Ensembl: ENSG00000124813  HGNC: 10472  HPRD: 02566 
OTX2orthodenticle homeobox 2 Entrez:5015  HGNC: 8522  HPRD: 07190  Ensembl: ENSG00000165588 
SPRY2sprouty homolog 2 (Drosophila) Entrez:10253  Ensembl: ENSG00000136158  HPRD: 03916  HGNC: 11270 
DUSP6dual specificity phosphatase 6 Entrez:1848  HGNC: 3072  HPRD: 04124  Ensembl: ENSG00000139318 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
FGFR2fibroblast growth factor receptor 2
RUNX2runt-related transcription factor 2
OTX2orthodenticle homeobox 2
SPRY2sprouty homolog 2 (Drosophila)
DUSP6dual specificity phosphatase 6
Query geneGeneGene descriptionEdge score
FGFR2FGFR2fibroblast growth factor receptor 2
RUNX2RUNX2runt-related transcription factor 2
OTX2OTX2orthodenticle homeobox 2
SPRY2SPRY2sprouty homolog 2 (Drosophila)
DUSP6DUSP6dual specificity phosphatase 6

Troyanskaya Laboratory - Princeton University