ASD

GO:0070997 neuron death (20)

GeneInput weightStandardRank
GRIK20.51142
SIAH1--550
PARK20.251634
ERBB3--921
GAPDH--1244
PPARGC1A--1920
APP--1991
BCL20.2512759
BAG5--2959
TNFRSF21--3149
MAX--5628
POU4F3--16147
BNIP3--6611
LRRK2--113335
BID--14222
LIG4--115324
ZNF746--20550
PIGT--20842
NLRP1--22465
AIFM1--25695

Network

GO:0070997

Network
Enrichment
NameDescriptionExternal IDs
GRIK2glutamate receptor, ionotropic, kainate 2 Entrez:2898  Ensembl: ENSG00000164418  HGNC: 4580  HPRD: 00692 
SIAH1siah E3 ubiquitin protein ligase 1 Entrez:6477  Ensembl: ENSG00000196470  HGNC: 10857  HPRD: 03736 
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin) Entrez:5071  HPRD: 03967  HGNC: 8607  Ensembl: ENSG00000185345 
ERBB3v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 Entrez:2065  HGNC: 3431  Ensembl: ENSG00000065361  HPRD: 01820 
GAPDHglyceraldehyde-3-phosphate dehydrogenase Entrez:2597  HPRD: 00713  Ensembl: ENSG00000111640  HGNC: 4141 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GRIK2glutamate receptor, ionotropic, kainate 2
SIAH1siah E3 ubiquitin protein ligase 1
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)
ERBB3v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
GAPDHglyceraldehyde-3-phosphate dehydrogenase
Query geneGeneGene descriptionEdge score
GRIK2GRIK2glutamate receptor, ionotropic, kainate 2
SIAH1SIAH1siah E3 ubiquitin protein ligase 1
PARK2PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)
ERBB3ERBB3v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3
GAPDHGAPDHglyceraldehyde-3-phosphate dehydrogenase

Troyanskaya Laboratory - Princeton University