ASD

GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation (18)

GeneInput weightStandardRank
ACVR1B--510
BMPR2--1964
BMP7--987
GDF6--11929
BMPR1A--2059
SMAD4--2927
BMP10--3196
BMP6--3242
BMP2--13686
BMP4--15180
TGFB3--15321
TGFBR1--16027
GDF7--7494
GDF2--11942
TGFB10.25114736
RBPMS--16365
ENG--117647
TTK--25644

Network

GO:0010862

Network
Enrichment
NameDescriptionExternal IDs
ACVR1Bactivin A receptor, type IB Entrez:91  Ensembl: ENSG00000135503  HGNC: 172  HPRD: 03193 
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) Entrez:659  Ensembl: ENSG00000204217  HPRD: 02880  HGNC: 1078 
BMP7bone morphogenetic protein 7 Entrez:655  Ensembl: ENSG00000101144  HGNC: 1074  HPRD: 00212 
GDF6growth differentiation factor 6 Entrez:392255  HGNC: 4221  HPRD: 11002  Ensembl: ENSG00000156466 
BMPR1Abone morphogenetic protein receptor, type IA Entrez:657  HGNC: 1076  Ensembl: ENSG00000107779  HPRD: 03192 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ACVR1Bactivin A receptor, type IB
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
BMP7bone morphogenetic protein 7
GDF6growth differentiation factor 6
BMPR1Abone morphogenetic protein receptor, type IA
Query geneGeneGene descriptionEdge score
ACVR1BACVR1Bactivin A receptor, type IB
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
BMP7BMP7bone morphogenetic protein 7
GDF6GDF6growth differentiation factor 6
BMPR1ABMPR1Abone morphogenetic protein receptor, type IA

Troyanskaya Laboratory - Princeton University