ASD

GO:0010907 positive regulation of glucose metabolic process (23)

GeneInput weightStandardRank
AKT10.251303
HIF1A--1008
IRS1--11052
ARPP19--1432
IRS2--11607
PPARGC1A--1920
IGF10.2511993
GCK--12874
AKT2--13025
DYRK2--3180
PTH--5481
ADRA1B0.2515964
SORBS1--6543
GAPDHS--6782
C1QTNF2--7354
PMAIP1--7387
MLXIPL--10379
INSR--110986
STK11--111332
HNF4A--112281
INS--119021
IGF20.25123391
ARNT--24282

Network

GO:0010907

Network
Enrichment
NameDescriptionExternal IDs
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Entrez:3091  HGNC: 4910  Ensembl: ENSG00000100644  HPRD: 04517 
IRS1insulin receptor substrate 1 Entrez:3667  HPRD: 00943  HGNC: 6125 
ARPP19cAMP-regulated phosphoprotein, 19kDa Entrez:10776  Ensembl: ENSG00000128989  HGNC: 16967  HPRD: 09264 
IRS2insulin receptor substrate 2 Entrez:8660  HPRD: 02878  HGNC: 6126  Ensembl: ENSG00000185950 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
AKT1v-akt murine thymoma viral oncogene homolog 1
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
IRS1insulin receptor substrate 1
ARPP19cAMP-regulated phosphoprotein, 19kDa
IRS2insulin receptor substrate 2
Query geneGeneGene descriptionEdge score
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1
HIF1AHIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
IRS1IRS1insulin receptor substrate 1
ARPP19ARPP19cAMP-regulated phosphoprotein, 19kDa
IRS2IRS2insulin receptor substrate 2

Troyanskaya Laboratory - Princeton University