ASD

GO:0071634 regulation of transforming growth factor-beta production (16)

GeneInput weightStandardRank
TGFB2--625
CREB1--991
HIF1A--1008
ATF2--1137
SMAD3--1541
SMAD4--2927
PTGS20.2513176
WNT11--4528
FURIN--4868
FOXP3--16270
XCL1--6562
IL13--7741
GATA6--113349
CD24--113608
THBS1--21993
ATP6AP2--24552

Network

GO:0071634

Network
Enrichment
NameDescriptionExternal IDs
TGFB2transforming growth factor, beta 2 Entrez:7042  HGNC: 11768  Ensembl: ENSG00000092969  HPRD: 01828 
CREB1cAMP responsive element binding protein 1 Entrez:1385  HGNC: 2345  HPRD: 00442  Ensembl: ENSG00000118260 
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Entrez:3091  HGNC: 4910  Ensembl: ENSG00000100644  HPRD: 04517 
ATF2activating transcription factor 2 Entrez:1386  Ensembl: ENSG00000115966  HPRD: 00443  HGNC: 784 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
TGFB2transforming growth factor, beta 2
CREB1cAMP responsive element binding protein 1
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
ATF2activating transcription factor 2
SMAD3SMAD family member 3
Query geneGeneGene descriptionEdge score
TGFB2TGFB2transforming growth factor, beta 2
CREB1CREB1cAMP responsive element binding protein 1
HIF1AHIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
ATF2ATF2activating transcription factor 2
SMAD3SMAD3SMAD family member 3

Troyanskaya Laboratory - Princeton University