ASD

GO:0006939 smooth muscle contraction (32)

GeneInput weightStandardRank
KCNMA10.25187
SSTR2--185
PDE4D--357
DRD10.251662
ADRA1A--937
EDNRB--11322
EDN3--11522
FKBP1B--1700
DRD20.2512071
EDNRA--13271
AGT--13783
TSHZ3--4327
GDNF--14462
KNG1--5045
HTR2B--5233
HTR1D0.2517287
TACR1--7688
CNN3--7711
MYL7--8005
TRPV10.2518765
EDN1--9566
GAL--9612
BDKRB2--10260
DLG1--10557
P2RX3--11797
NMUR1--13186
EDN2--13347
ACTA2--114346
CHRNB20.25120277
SMTN--21972
TPCN2--24098
MYH11--124412

Network

GO:0006939

Network
Enrichment
NameDescriptionExternal IDs
KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1 Entrez:3778  Ensembl: ENSG00000156113  HGNC: 6284  HPRD: 15967 
SSTR2somatostatin receptor 2 Entrez:6752  HPRD: 01674  HGNC: 11331 
PDE4Dphosphodiesterase 4D, cAMP-specific Entrez:5144  HPRD: 02530  HGNC: 8783  Ensembl: ENSG00000113448 
DRD1dopamine receptor D1 Entrez:1812  HPRD: 00538  HGNC: 3020  Ensembl: ENSG00000184845 
ADRA1Aadrenoceptor alpha 1A Entrez:148  HGNC: 277  Ensembl: ENSG00000120907  HPRD: 00081 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1
SSTR2somatostatin receptor 2
PDE4Dphosphodiesterase 4D, cAMP-specific
DRD1dopamine receptor D1
ADRA1Aadrenoceptor alpha 1A
Query geneGeneGene descriptionEdge score
KCNMA1KCNMA1potassium large conductance calcium-activated channel, subfamily M, alpha member 1
SSTR2SSTR2somatostatin receptor 2
PDE4DPDE4Dphosphodiesterase 4D, cAMP-specific
DRD1DRD1dopamine receptor D1
ADRA1AADRA1Aadrenoceptor alpha 1A

Troyanskaya Laboratory - Princeton University