ASD

GO:0071396 cellular response to lipid (21)

GeneInput weightStandardRank
GRIN2A0.25156
SFRP1--204
GRIN2B1.01599
LRP6--778
PIK3R10.2511065
BAD--1647
INHBB--2840
EGR1--3527
PTGDR--5892
TNFSF4--6034
HMGCS1--6431
CYP7A10.2516478
APOB--8237
AACS--9069
INHBA--9731
HMGCS2--10713
PDGFB--12484
CPS1--112985
E2F1--13572
ASS1--123526
CCNB1--24648

Network

GO:0071396

Network
Enrichment
NameDescriptionExternal IDs
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B Entrez:2904  Ensembl: ENSG00000150086  HPRD: 00697  HGNC: 4586 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HGNC: 8979  Ensembl: ENSG00000145675  HPRD: 01381 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
SFRP1secreted frizzled-related protein 1
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B
LRP6low density lipoprotein receptor-related protein 6
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
Query geneGeneGene descriptionEdge score
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
SFRP1SFRP1secreted frizzled-related protein 1
GRIN2BGRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B
LRP6LRP6low density lipoprotein receptor-related protein 6
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)

Troyanskaya Laboratory - Princeton University