ASD

GO:0000578 embryonic axis specification (26)

GeneInput weightStandardRank
PCSK6--731
PTCH1--11149
CXXC4--1472
CITED1--1867
SMAD6--2079
T--2584
WNT5A--2870
SMAD4--2927
WNT1--3263
EPB41L5--3311
HOXB6--3623
TBX3--3843
C2CD3--5468
CTNNB10.2516229
WNT7A--6375
TDRD5--6427
HOXD8--6575
TDGF1--6833
RIPPLY2--7060
SMAD2--7224
RIPPLY1--8488
GDF3--19473
FRS2--12610
TCF7L1--13850
FZD5--21891
PLD6--22708

Network

GO:0000578

Network
Enrichment
NameDescriptionExternal IDs
PCSK6proprotein convertase subtilisin/kexin type 6 Entrez:5046  HPRD: 01329  HGNC: 8569  Ensembl: ENSG00000140479 
PTCH1patched 1 Entrez:5727  Ensembl: ENSG00000185920  HGNC: 9585  HPRD: 03200 
CXXC4CXXC finger protein 4 Entrez:80319  HPRD: 16773  HGNC: 24593  Ensembl: ENSG00000168772 
CITED1Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 Entrez:4435  HGNC: 1986  HPRD: 02146  Ensembl: ENSG00000125931 
SMAD6SMAD family member 6 Entrez:4091  Ensembl: ENSG00000137834  HPRD: 04240  HGNC: 6772 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PCSK6proprotein convertase subtilisin/kexin type 6
PTCH1patched 1
CXXC4CXXC finger protein 4
CITED1Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
SMAD6SMAD family member 6
Query geneGeneGene descriptionEdge score
PCSK6PCSK6proprotein convertase subtilisin/kexin type 6
PTCH1PTCH1patched 1
CXXC4CXXC4CXXC finger protein 4
CITED1CITED1Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
SMAD6SMAD6SMAD family member 6

Troyanskaya Laboratory - Princeton University