ASD

GO:0021532 neural tube patterning (26)

GeneInput weightStandardRank
PAX60.251355
LRP6--778
WNT10B--1030
PTCH1--11149
FOXA2--1835
PAX7--12033
BMI1--2175
WNT1--3263
GBX2--3588
EN1--3999
WNT3--4799
WNT3A--4844
BMP4--15180
HES10.2515662
SMO0.2515864
MNX1--5932
GAS1--5960
GSC--8075
TULP3--8569
KDM2B--8663
HES3--8916
GLI3--19032
SHH--115942
RPGRIP1L--19545
PSEN1--20241
PSEN2--21431

Network

GO:0021532

Network
Enrichment
NameDescriptionExternal IDs
PAX6paired box 6 Entrez:5080  HPRD: 06167  Ensembl: ENSG00000007372  HGNC: 8620 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
WNT10Bwingless-type MMTV integration site family, member 10B Entrez:7480  Ensembl: ENSG00000169884  HGNC: 12775  HPRD: 03548 
PTCH1patched 1 Entrez:5727  Ensembl: ENSG00000185920  HGNC: 9585  HPRD: 03200 
FOXA2forkhead box A2 Entrez:3170  HGNC: 5022  Ensembl: ENSG00000125798  HPRD: 02618 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PAX6paired box 6
LRP6low density lipoprotein receptor-related protein 6
WNT10Bwingless-type MMTV integration site family, member 10B
PTCH1patched 1
FOXA2forkhead box A2
Query geneGeneGene descriptionEdge score
PAX6PAX6paired box 6
LRP6LRP6low density lipoprotein receptor-related protein 6
WNT10BWNT10Bwingless-type MMTV integration site family, member 10B
PTCH1PTCH1patched 1
FOXA2FOXA2forkhead box A2

Troyanskaya Laboratory - Princeton University