ASD

GO:0051057 positive regulation of small GTPase mediated signal transduction (26)

GeneInput weightStandardRank
KRAS--1143
RELN0.51436
MAP2K10.251474
DGKI--807
SHOC2--974
RAC1--1087
IGF10.2511993
LPAR1--2975
KITLG--3019
CSF1--3235
CDON--3482
FGF10--14373
NRAS--15506
ABRA--6916
GPR55--7357
RASGRP4--7359
ITPKB--7886
NOTCH2--19863
EPO--12314
ALS2--112325
F2R--12498
HRAS0.25112845
LPAR2--14606
F2RL1--15088
ARRB1--19005
ERBB2--121638

Network

GO:0051057

Network
Enrichment
NameDescriptionExternal IDs
KRASKirsten rat sarcoma viral oncogene homolog Entrez:3845  Ensembl: ENSG00000133703  HGNC: 6407  HPRD: 01817 
RELNreelin Entrez:5649  HGNC: 9957  Ensembl: ENSG00000189056  HPRD: 02742 
MAP2K1mitogen-activated protein kinase kinase 1 Entrez:5604  HGNC: 6840  HPRD: 01469 
DGKIdiacylglycerol kinase, iota Entrez:9162  HPRD: 07238  HGNC: 2855  Ensembl: ENSG00000157680 
SHOC2soc-2 suppressor of clear homolog (C. elegans) Entrez:8036  Ensembl: ENSG00000108061  HGNC: 15454  HPRD: 04144 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
KRASKirsten rat sarcoma viral oncogene homolog
RELNreelin
MAP2K1mitogen-activated protein kinase kinase 1
DGKIdiacylglycerol kinase, iota
SHOC2soc-2 suppressor of clear homolog (C. elegans)
Query geneGeneGene descriptionEdge score
KRASKRASKirsten rat sarcoma viral oncogene homolog
RELNRELNreelin
MAP2K1MAP2K1mitogen-activated protein kinase kinase 1
DGKIDGKIdiacylglycerol kinase, iota
SHOC2SHOC2soc-2 suppressor of clear homolog (C. elegans)

Troyanskaya Laboratory - Princeton University