ASD

GO:0060766 negative regulation of androgen receptor signaling pathway (9)

GeneInput weightStandardRank
SFRP1--204
SMARCA4--751
SIRT1--1656
IGF10.2511993
TCF21--5065
HDAC1--5284
PIAS2--5654
HEYL--10561
PHB--123909

Network

GO:0060766

Network
Enrichment
NameDescriptionExternal IDs
SFRP1secreted frizzled-related protein 1 Entrez:6422  HPRD: 09165  Ensembl: ENSG00000104332  HGNC: 10776 
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Entrez:6597  HPRD: 04459  HGNC: 11100  Ensembl: ENSG00000127616 
SIRT1sirtuin 1 Entrez:23411  Ensembl: ENSG00000096717  HPRD: 08381  HGNC: 14929 
IGF1insulin-like growth factor 1 (somatomedin C) Entrez:3479  HPRD: 00936  Ensembl: ENSG00000017427  HGNC: 5464 
TCF21transcription factor 21 Entrez:6943  HGNC: 11632  HPRD: 04493  Ensembl: ENSG00000118526 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SFRP1secreted frizzled-related protein 1
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SIRT1sirtuin 1
IGF1insulin-like growth factor 1 (somatomedin C)
TCF21transcription factor 21
Query geneGeneGene descriptionEdge score
SFRP1SFRP1secreted frizzled-related protein 1
SMARCA4SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SIRT1SIRT1sirtuin 1
IGF1IGF1insulin-like growth factor 1 (somatomedin C)
TCF21TCF21transcription factor 21

Troyanskaya Laboratory - Princeton University