ASD

GO:0045862 positive regulation of proteolysis (58)

GeneInput weightStandardRank
SUMO1--178
AKT10.251303
CNTN2--438
TRIB2--534
CSNK1D--811
UBE2V2--1207
OGT--1215
CSNK1E0.2511225
EP300--11256
SMAD7--1283
HDAC2--1413
ADRA2A0.2511556
FBXW11--1610
RCHY1--1845
PSMD10--2012
PTEN1.012260
BTRC--2430
SUMO2--2503
STUB1--3156
TRIB1--3331
MGEA5--3440
RNF180--3828
VCP--4121
C6--4835
FURIN--4868
IFNG--15255
PRICKLE1--15311
MDM2--5588
IL1B--16220
HSPBP1--6359
DNAJB2--7177
USP5--7638
SH3D19--7820
WFS10.2518575
KLKB1--12237
TRIM320.25112319
IFT88--12821
LRRK2--113335
GCLC--13506
AURKAIP1--14704
IFT52--16550
F12--118401
TNF0.25119823
PSEN1--20241
PACSIN3--20292
TAF1--20307
ADAM8--20729
APOE0.25121310
GNB2L1--22873
NUB1--23472
NRD1--24048
PLGRKT--24128
FBXO22--24394
ADAM9--124801
DAB2--24837
CLU--24939
CLN6--125203
PLK1--25689

Network

GO:0045862

Network
Enrichment
NameDescriptionExternal IDs
SUMO1small ubiquitin-like modifier 1 Entrez:7341  Ensembl: ENSG00000116030  HGNC: 12502  HPRD: 03554 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
CNTN2contactin 2 (axonal) Entrez:6900  HGNC: 2172  Ensembl: ENSG00000184144  HPRD: 01826 
TRIB2tribbles homolog 2 (Drosophila) Entrez:28951  HPRD: 18224  HGNC: 30809  Ensembl: ENSG00000071575 
CSNK1Dcasein kinase 1, delta Entrez:1453  Ensembl: ENSG00000141551  HGNC: 2452  HPRD: 02920 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SUMO1small ubiquitin-like modifier 1
AKT1v-akt murine thymoma viral oncogene homolog 1
CNTN2contactin 2 (axonal)
TRIB2tribbles homolog 2 (Drosophila)
CSNK1Dcasein kinase 1, delta
Query geneGeneGene descriptionEdge score
SUMO1SUMO1small ubiquitin-like modifier 1
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1
CNTN2CNTN2contactin 2 (axonal)
TRIB2TRIB2tribbles homolog 2 (Drosophila)
CSNK1DCSNK1Dcasein kinase 1, delta

Troyanskaya Laboratory - Princeton University