ASD

GO:0050886 endocrine process (27)

GeneInput weightStandardRank
MEG3--201
RPS6KA20.251711
NOX1--1232
AGTR20.2511418
EDN3--11522
FZD4--11666
CGA0.2511927
NKX2-1--2488
DRD30.2512757
AGTR1--12898
CYBA--13439
AGT--13783
CORIN--3841
TBX3--3843
REN--16631
ACE--9212
GHRL0.2519333
EDN1--9566
INHBA--9731
ACE2--10229
HSD11B2--10731
CYP11B2--11354
PCSK5--12160
NOS3--12710
EDN2--13347
ECE1--120668
ATP6AP2--24552

Network

GO:0050886

Network
Enrichment
NameDescriptionExternal IDs
MEG3maternally expressed 3 (non-protein coding) Entrez:55384  HGNC: 14575  Ensembl: ENSG00000214548 
RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 2 Entrez:6196  Ensembl: ENSG00000071242  HPRD: 03403  HGNC: 10431 
NOX1NADPH oxidase 1 Entrez:27035  HGNC: 7889  Ensembl: ENSG00000007952  HPRD: 02203 
AGTR2angiotensin II receptor, type 2 Entrez:186  HPRD: 02071  HGNC: 338  Ensembl: ENSG00000180772 
EDN3endothelin 3 Entrez:1908  HGNC: 3178  Ensembl: ENSG00000124205  HPRD: 00570 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MEG3maternally expressed 3 (non-protein coding)
RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 2
NOX1NADPH oxidase 1
AGTR2angiotensin II receptor, type 2
EDN3endothelin 3
Query geneGeneGene descriptionEdge score
MEG3MEG3maternally expressed 3 (non-protein coding)
RPS6KA2RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 2
NOX1NOX1NADPH oxidase 1
AGTR2AGTR2angiotensin II receptor, type 2
EDN3EDN3endothelin 3

Troyanskaya Laboratory - Princeton University