ASD

GO:0043525 positive regulation of neuron apoptosis (33)

GeneInput weightStandardRank
UBE2M--148
ASCL1--229
NF10.251333
CDK5R1--406
SRPK2--412
NR3C1--463
TGFB2--625
JUN--647
EPHA7--914
HRK--1059
MUSK--2237
FASLG--12766
CDK50.2513113
BCL2L11--5454
AGRN0.2515611
PTPRF--6764
BAX--7313
PMAIP1--7387
PCSK9--8260
MAP2K7--8382
RHOC--9929
ATM--110590
CASP2--12965
RAPSN--13568
ITGA1--13957
TNF0.25119823
NCF2--121812
TP530.25121968
IL18--22799
MAP3K11--23341
CASP7--24086
CASP6--24423
NQO1--24933

Network

GO:0043525

Network
Enrichment
NameDescriptionExternal IDs
UBE2Mubiquitin-conjugating enzyme E2M Entrez:9040  HPRD: 04414  HGNC: 12491  Ensembl: ENSG00000130725 
ASCL1achaete-scute complex homolog 1 (Drosophila) Entrez:429  HPRD: 00011  Ensembl: ENSG00000139352  HGNC: 738 
NF1neurofibromin 1 Entrez:4763  HGNC: 7765  HPRD: 01203  Ensembl: ENSG00000196712 
CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35) Entrez:8851  Ensembl: ENSG00000176749  HGNC: 1775  HPRD: 04586 
SRPK2SRSF protein kinase 2 Entrez:6733  HPRD: 04280  Ensembl: ENSG00000135250  HGNC: 11306 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
UBE2Mubiquitin-conjugating enzyme E2M
ASCL1achaete-scute complex homolog 1 (Drosophila)
NF1neurofibromin 1
CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35)
SRPK2SRSF protein kinase 2
Query geneGeneGene descriptionEdge score
UBE2MUBE2Mubiquitin-conjugating enzyme E2M
ASCL1ASCL1achaete-scute complex homolog 1 (Drosophila)
NF1NF1neurofibromin 1
CDK5R1CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35)
SRPK2SRPK2SRSF protein kinase 2

Troyanskaya Laboratory - Princeton University