ASD

GO:0051348 negative regulation of transferase activity (140)

GeneInput weightStandardRank
PPP2CA--21
RGS4--99
AKT10.251303
UCHL1--1317
MAPK8IP1--1326
NF10.251333
DRD50.251482
GNAQ--490
APC0.251528
TRIB2--534
SPRED2--643
DRD10.251662
LRP6--778
DUSP8--796
PPP2R1A--852
PKIA--959
BMP7--987
THY1--993
CDKN1B--1067
SPRED1--1282
DUSP5--1317
SPRY2--1552
IRS2--11607
SRCIN1--1623
YWHAG--1799
DUSP6--1889
GPS1--2030
HMGCR--2128
DUSP1--2140
PTEN1.012260
GSK3A--2346
ABL1--2653
ILK--2917
LATS1--3031
SPECC1L--3048
TRIB1--3331
RB1--13450
SH3BP5--3494
SPRY4--3540
TERF1--3607
DAB2IP--3635
RGS2--3677
GADD45A--4101
PDPK1--4150
DUSP4--4300
IL6--14578
NR2F2--4609
CDKN1A--4620
GCKR--4760
NF2--14798
CDKN1C--14821
ADIPOQ0.2514834
PDCD4--4897
DUSP19--5073
BMP4--15180
PAK2--5515
MYOCD--5769
PRKCD--5824
DUSP3--5845
GADD45B--6021
DUSP10--6196
IL1B--16220
TFAP4--6483
PRKAG2--16710
MEN1--16723
PTPRJ--17218
DUSP7--7411
ERRFI1--7414
DUSP9--7653
PPP2R5A--7723
DUSP2--7903
ZFYVE28--8207
PYDC1--8236
HEXIM1--8261
NUP62--19343
DEPTOR--9420
ADORA2A0.2519605
CDKN2A--19650
DUSP16--9952
GSTP10.25110429
SPRY1--10579
CAV3--110580
MBIP--10795
LAX1--10896
INPPL1--11037
TAF7--11048
PKIB--11257
RGS14--11308
TSC20.25111448
HIPK3--11588
DBNDD2--12469
AKT1S1--12840
PIF1--13408
IRAK3--14013
CRIPAK--14378
LATS2--15008
ZNF675--15034
PTPRC--15053
STK380.25115423
HSPB1--115779
TP73--15964
TRIB3--16821
LRP5--116985
SPRED3--19822
AJUBA--19840
PKIG--20074
PSEN1--20241
GPS2--20293
KAT2B--20429
HEXIM2--20619
PRDX3--20779
CBLC--20918
FABP4--21076
DVL1--21155
APOE0.25121310
RGS3--21940
PPARG--121945
CLN8--121998
ZGPAT--22147
POT1--22291
WWTR1--22777
SNX6--22785
GNB2L1--22873
PRKRIP1--22886
IBTK--23069
PINX1--23265
SMPD1--124037
NPRL2--24088
CDK5RAP1--24534
GBA--124709
CAV1--124767
FGFR1OP--24938
TARBP2--24987
AIDA--25079
CHORDC1--25131
DUSP22--25132
PML--25248
SFN--25432
DNAJA3--25641
PLK1--25689

Network

GO:0051348

Network
Enrichment
NameDescriptionExternal IDs
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme Entrez:5515  HGNC: 9299  HPRD: 08912 
RGS4regulator of G-protein signaling 4 Entrez:5999  HGNC: 10000  HPRD: 03947  Ensembl: ENSG00000117152 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) Entrez:7345  HPRD: 01877  HGNC: 12513  Ensembl: ENSG00000154277 
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 1 Entrez:9479  HPRD: 05223  Ensembl: ENSG00000121653  HGNC: 6882 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
RGS4regulator of G-protein signaling 4
AKT1v-akt murine thymoma viral oncogene homolog 1
UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 1
Query geneGeneGene descriptionEdge score
PPP2CAPPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
RGS4RGS4regulator of G-protein signaling 4
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1
UCHL1UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
MAPK8IP1MAPK8IP1mitogen-activated protein kinase 8 interacting protein 1

Troyanskaya Laboratory - Princeton University