ASD

GO:0043434 response to peptide hormone stimulus (354)

GeneInput weightStandardRank
GNB1--15
YWHAB0.25145
PLCB1--161
ATP6V0B--84
ADCY2--102
KRAS--1143
ABCC8--1161
FGFR2--1165
GNB2--169
FGF9--241
ATP6V1G2--247
ATP6V0D1--258
GNG4--277
MAP1B--300
AKT10.251303
SHC3--330
ATP6V0C0.251350
NR3C1--463
ADCY10.251466
MAP2K10.251474
PKM--501
CCKBR--533
PRKACB--544
GNG3--591
NR4A3--1594
GRIN2B1.01599
PCSK1--604
IGF1R--631
DRD10.251662
CCND2--689
VLDLR0.251837
ERBB3--921
ATP6V1A--981
MAPK1--985
FGF1--1005
HIF1A--1008
JUNB--1044
IRS1--11052
PIK3R10.2511065
MAP2K20.2511066
DLC1--1105
CAB39--1116
PRKCI--1135
PRKAR1B--1163
VGF0.2511243
PTPRN--1248
BTG1--1268
FYN--1284
CDO1--1319
RELA--1352
BSG--1355
AR0.2511499
PRKAR2B--1512
ATP6V1F--1557
ATP6V1B2--1583
IRS2--11607
FGF5--1645
FGFR3--11648
PIK3R3--1659
ALDOB--1669
GNG13--1713
NR0B1--11715
PRKAR1A--11718
BAIAP20.2511725
ATP6V0A1--1748
FOXA2--1835
TSC10.2511844
GAB1--1864
CITED1--1867
ADCY8--1906
FGF7--1995
GRB10--2023
EIF4E0.2512043
STS0.2512045
GHSR0.2512085
RBP4--2097
SHC2--2147
STC2--2176
AP3S1--2254
TIMP1--2285
GHRHR--2312
GSK3A--2346
GNAS--12352
POR0.2512359
CFTR--12414
ADCY9--2435
FGFR1--2550
STAT3--12598
EIF4G1--2657
GRB2--2662
HDAC5--2683
UBE2B--2708
BCL20.2512759
RPS6KB1--2773
PIK3CA0.2512782
INHBB--2840
GCK--12874
FGF23--12939
FOXO3--2950
AKT2--13025
PDE3B--3088
GNG7--3138
NKX6-1--3174
SOS1--13181
FGF3--3192
ATP6V1E1--3217
WNT1--3263
SMARCC1--3276
MC4R0.2513280
MAS1--3300
FGF20--3325
PRKACG--3335
GNG2--3365
GCGR--13430
BTG2--3504
SFRP4--3511
EGR1--3527
F7--3543
SLC2A2--3601
MET1.013618
KL--3641
DAG1--3662
SRD5A10.2513730
FABP30.2513742
NGF0.2513749
HDAC9--3770
STAT5B--3888
RHEB--3911
PRKAA2--3958
GIP--3965
OTC--13989
EGR20.2514059
SCAP--4068
GNG5--4079
IGFBP1--4094
PDPK1--4150
ACVR1C--4200
GCG--4286
LDLR--4311
PNLIPRP1--4320
SOCS7--4328
ADCY5--4352
PNLIP--4356
ADCY6--4362
FGF10--14373
PLA2G1B--4440
CRK--4478
OXTR0.514494
CYP11A10.2514559
GH1--4570
IL6--14578
ADCY3--4618
SERPINA7--4628
FGF8--14677
FGF18--4736
ATP6V1G3--4739
FGF4--4827
ADIPOQ0.2514834
DBH0.2514946
ATP6V1H--4958
PKLR--5039
PPM1A--5058
FGF17--5059
PXN--5215
LPIN1--5282
LYN--5289
GNB3--15407
AQP2--5462
PIK3R2--5501
NRAS--15506
PAK1--5556
RAF10.2515559
PRKAB2--5613
MAX--5628
SI--5640
ENPP1--15674
PPARA--5743
SHC1--5839
NPPB--5967
SOCS2--6071
MAPK30.2516096
GALP--6237
ABCC5--6253
GPAM--6297
ATP6V0A4--6347
AANAT0.2516439
TH0.2516482
PCK1--6492
SORBS1--6543
GNG8--6588
FGF16--6612
PRKAG2--16710
FOXO10.2516970
CAPN10--7136
ATP6V0E2--7188
CXCL12--7204
CYP21A20.2517267
TLR4--17283
ANXA1--7465
MLST8--7510
KHK--7555
CACYBP--7615
ATP6V1G1--7665
PIK3R4--7682
IL10--17883
NUDC--8087
GJA10.2518195
PCSK9--8260
FOXC2--8308
ATP6V0D2--8341
ADCY4--8354
AKAP1--8358
APOBEC1--8376
AHSG--8418
KLB--8419
EREG--8504
STRADA--8555
TRPV10.2518765
PRKACA--8797
PFKFB1--8815
PIK3C3--8907
PRKAG3--9028
USF1--9041
GATM--19468
ATP6V1B1--9514
GAL--9612
FGF2--9627
STXBP4--9641
PTPN2--9960
SOCS1--9996
OXT0.25110022
GHR--110058
PIK3CB--10067
PTPN11--110178
APPL1--10194
FOXO4--10242
BCAR1--10308
FGF19--10321
GSTP10.25110429
TFF1--10558
NPPA--110598
HMGCS2--10713
UCP3--110723
HSD11B2--10731
ADM--10761
FAS--110857
FGF6--10907
INSR--110986
INPPL1--11037
PTK20.25111177
STK11--111332
TSC20.25111448
FADS1--11633
GNB4--11845
GNG12--11929
RPTOR--12241
TFF3--12246
INSIG2--12416
ATP6V1C2--12433
TLR9--12436
HHEX--12438
PDGFB--12484
FRS2--12610
ATP6V1E2--12621
BRAF--112672
FOXO6--12694
NOS3--12710
HRAS0.25112845
CPS1--112985
CAB39L--13180
SORT1--13249
LEP0.25113368
SH2B2--13396
GGH--13518
PLAT--13559
FBP1--113717
ZNF106--13720
SLC2A8--13742
PHIP--13849
FZD2--13981
ARG1--114097
ATP6V0A2--14249
PRKCQ--14566
ATP6V1D--14824
TIMP4--14828
RXRA0.25115046
RHOQ--15107
RETN0.25115196
FOXS1--15328
MTOR--15435
QDPR0.25115452
SOCS3--15768
FGF22--16297
TRIB3--16821
SREBF1--16874
EIF4EBP1--17707
INS--119021
STAT5A--19316
PLD1--19789
JAK2--120033
UCP2--20042
KAT2B--20429
EIF4EBP2--20602
PARP1--20642
GNG10--20887
TRIM16--21315
PRKAR2A--21408
CCL5--21529
STRADB--21620
TCIRG1--121664
IRF1--121687
IL6R--21793
GNG11--21818
CTGF--21927
PPARG--121945
FZD1--22086
SLC27A1--22268
PRKAB1--22392
CYC1--22427
FGFR4--22438
IL18--22799
ACSL5--23022
EIF2B1--23040
PLD2--23098
ATP6V1C1--23277
IGF20.25123391
LTA4H--23444
ASS1--123526
BDH1--23717
PRSS8--23819
PRKAG1--23828
SLC29A2--23945
THEM4--23999
CDK1--24001
DOK1--24151
GOT1--24315
PRKAA1--24385
SPARC--24433
COL1A1--124560
CTSB--24596
INPP5K--24643
EIF2B4--24721
EIF4B--24765
NR1H3--24805
PRKDC--24908
EEF2K--25001
ADCY7--25198
HADH--125281
ATP6V0E1--25295
EIF2B3--25409
EIF2B5--25537
EIF2B2--25563
RPS6--25635
PPAT--25757

Network

GO:0043434

Network
Enrichment
NameDescriptionExternal IDs
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1 Entrez:2782  HGNC: 4396  HPRD: 00766  Ensembl: ENSG00000078369 
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Entrez:7529  HGNC: 12849  Ensembl: ENSG00000166913  HPRD: 03184 
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HGNC: 15917  HPRD: 06177  Ensembl: ENSG00000182621 
ATP6V0BATPase, H+ transporting, lysosomal 21kDa, V0 subunit b Entrez:533  Ensembl: ENSG00000117410  HGNC: 861  HPRD: 04759 
ADCY2adenylate cyclase 2 (brain) Entrez:108  HGNC: 233  HPRD: 00052  Ensembl: ENSG00000078295 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
ATP6V0BATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
ADCY2adenylate cyclase 2 (brain)
Query geneGeneGene descriptionEdge score
GNB1GNB1guanine nucleotide binding protein (G protein), beta polypeptide 1
YWHABYWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
ATP6V0BATP6V0BATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
ADCY2ADCY2adenylate cyclase 2 (brain)

Troyanskaya Laboratory - Princeton University