ASD

GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal (30)

GeneInput weightStandardRank
DRD50.251482
RPS6KA20.251711
ADRB1--866
ADRA1A--937
NOX1--1232
AGTR20.2511418
EDN3--11522
ADRB3--11787
NKX2-1--2488
DRD30.2512757
AGTR1--12898
CYBA--13439
ADRA1D--3761
AGT--13783
CORIN--3841
ADRA1B0.2515964
REN--16631
ACE--9212
EDN1--9566
ACE2--10229
HSD11B2--10731
CYP11B2--11354
SOD2--12001
PCSK5--12160
NOS3--12710
EDN2--13347
ECE1--120668
ADRB20.25122718
TPM1--123549
ATP6AP2--24552

Network

GO:0003044

Network
Enrichment
NameDescriptionExternal IDs
DRD5dopamine receptor D5 Entrez:1816  HGNC: 3026  Ensembl: ENSG00000169676  HPRD: 00542 
RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 2 Entrez:6196  Ensembl: ENSG00000071242  HPRD: 03403  HGNC: 10431 
ADRB1adrenoceptor beta 1 Entrez:153  HGNC: 285  Ensembl: ENSG00000043591  HPRD: 00181 
ADRA1Aadrenoceptor alpha 1A Entrez:148  HGNC: 277  Ensembl: ENSG00000120907  HPRD: 00081 
NOX1NADPH oxidase 1 Entrez:27035  HGNC: 7889  Ensembl: ENSG00000007952  HPRD: 02203 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
DRD5dopamine receptor D5
RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 2
ADRB1adrenoceptor beta 1
ADRA1Aadrenoceptor alpha 1A
NOX1NADPH oxidase 1
Query geneGeneGene descriptionEdge score
DRD5DRD5dopamine receptor D5
RPS6KA2RPS6KA2ribosomal protein S6 kinase, 90kDa, polypeptide 2
ADRB1ADRB1adrenoceptor beta 1
ADRA1AADRA1Aadrenoceptor alpha 1A
NOX1NOX1NADPH oxidase 1

Troyanskaya Laboratory - Princeton University