ASD

GO:0032925 regulation of activin receptor signaling pathway (13)

GeneInput weightStandardRank
ACVR1B--510
FKBP1A--605
SMAD7--1283
ACVR2A--1768
LEMD3--12358
ACVR2B--13179
SKI--4231
FGF10--14373
MEN1--16723
FST--8021
INHBA--9731
ACVR1--111780
FSTL3--24700

Network

GO:0032925

Network
Enrichment
NameDescriptionExternal IDs
ACVR1Bactivin A receptor, type IB Entrez:91  Ensembl: ENSG00000135503  HGNC: 172  HPRD: 03193 
FKBP1AFK506 binding protein 1A, 12kDa Entrez:2280  Ensembl: ENSG00000088832  HGNC: 3711  HPRD: 01741 
SMAD7SMAD family member 7 Entrez:4092  HPRD: 04241  HGNC: 6773  Ensembl: ENSG00000101665 
ACVR2Aactivin A receptor, type IIA Entrez:92  HGNC: 173  HPRD: 00025  Ensembl: ENSG00000121989 
LEMD3LEM domain containing 3 Entrez:23592  Ensembl: ENSG00000174106  HGNC: 28887  HPRD: 09704 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ACVR1Bactivin A receptor, type IB
FKBP1AFK506 binding protein 1A, 12kDa
SMAD7SMAD family member 7
ACVR2Aactivin A receptor, type IIA
LEMD3LEM domain containing 3
Query geneGeneGene descriptionEdge score
ACVR1BACVR1Bactivin A receptor, type IB
FKBP1AFKBP1AFK506 binding protein 1A, 12kDa
SMAD7SMAD7SMAD family member 7
ACVR2AACVR2Aactivin A receptor, type IIA
LEMD3LEMD3LEM domain containing 3

Troyanskaya Laboratory - Princeton University