ASD

GO:0006942 regulation of striated muscle contraction (29)

GeneInput weightStandardRank
CACNA1G0.251149
ADORA1--498
RYR2--1862
NOS10.251908
ADRA1A--937
HDAC4--963
SMAD7--1283
ATP1A2--11611
FKBP1B--1700
CASQ1--2466
RGS2--3677
ATP1A10.2514084
ADRBK1--4864
NKX2-50.2515490
MEF2A--6060
MYBPC3--16241
MYL2--16261
ARG2--7159
MYBPH--8995
MYLK2--19540
CAV3--110580
MYL3--113896
SRI--15085
TNNI1--15390
DMPK0.25116840
P2RX4--20526
ATP2A1--121263
CTGF--21927
TNNT3--123680

Network

GO:0006942

Network
Enrichment
NameDescriptionExternal IDs
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit Entrez:8913  HPRD: 04961  HGNC: 1394  Ensembl: ENSG00000006283 
ADORA1adenosine A1 receptor Entrez:134  HPRD: 00042  Ensembl: ENSG00000163485  HGNC: 262 
RYR2ryanodine receptor 2 (cardiac) Entrez:6262  Ensembl: ENSG00000198626  HGNC: 10484  HPRD: 01619 
NOS1nitric oxide synthase 1 (neuronal) Entrez:4842  HPRD: 01226  HGNC: 7872  Ensembl: ENSG00000089250 
ADRA1Aadrenoceptor alpha 1A Entrez:148  HGNC: 277  Ensembl: ENSG00000120907  HPRD: 00081 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit
ADORA1adenosine A1 receptor
RYR2ryanodine receptor 2 (cardiac)
NOS1nitric oxide synthase 1 (neuronal)
ADRA1Aadrenoceptor alpha 1A
Query geneGeneGene descriptionEdge score
CACNA1GCACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit
ADORA1ADORA1adenosine A1 receptor
RYR2RYR2ryanodine receptor 2 (cardiac)
NOS1NOS1nitric oxide synthase 1 (neuronal)
ADRA1AADRA1Aadrenoceptor alpha 1A

Troyanskaya Laboratory - Princeton University