ASD

GO:0048701 embryonic cranial skeleton morphogenesis (30)

GeneInput weightStandardRank
NIPBL--1561
DLX20.2511235
PRRX1--1491
SMAD3--1541
LHX1--1926
TBX10.2512049
NODAL--12184
GNAS--12352
TFAP2A--12460
HOXA2--3750
TBX15--4012
SIX4--4623
BMP4--15180
TGFB3--15321
NDST1--5799
SMO0.2515864
GAS1--5960
TGFBR1--16027
TWIST1--16128
SIX2--6713
SMAD2--7224
CHST11--7380
FOXC2--8308
WNT9B--8495
TULP3--8569
RDH10--9600
TGFBR2--19756
TWIST2--14594
SIX1--115117
PRRX2--23414

Network

GO:0048701

Network
Enrichment
NameDescriptionExternal IDs
NIPBLNipped-B homolog (Drosophila) Entrez:25836  HPRD: 10560  HGNC: 28862  Ensembl: ENSG00000164190 
DLX2distal-less homeobox 2 Entrez:1746  Ensembl: ENSG00000115844  HGNC: 2915  HPRD: 00527 
PRRX1paired related homeobox 1 Entrez:5396  HPRD: 01337  HGNC: 9142  Ensembl: ENSG00000116132 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
LHX1LIM homeobox 1 Entrez:3975  HGNC: 6593  HPRD: 09067  Ensembl: ENSG00000132130 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NIPBLNipped-B homolog (Drosophila)
DLX2distal-less homeobox 2
PRRX1paired related homeobox 1
SMAD3SMAD family member 3
LHX1LIM homeobox 1
Query geneGeneGene descriptionEdge score
NIPBLNIPBLNipped-B homolog (Drosophila)
DLX2DLX2distal-less homeobox 2
PRRX1PRRX1paired related homeobox 1
SMAD3SMAD3SMAD family member 3
LHX1LHX1LIM homeobox 1

Troyanskaya Laboratory - Princeton University