ASD

GO:0007492 endoderm development (42)

GeneInput weightStandardRank
SOX2--1125
PTHLH--11269
DUSP5--1317
SMAD3--1541
FOXA2--1835
LHX1--1926
HOXC11--1946
BMPR1A--2059
DUSP1--2140
NODAL--12184
NKX2-1--2488
WNT8B--2506
SMAD4--2927
EPB41L5--3311
NOTCH1--13360
SOX17--3484
EXT10.2513907
DUSP4--4300
WNT11--4528
SOX7--4709
NANOG--4730
TBX20--16000
CTNNB10.2516229
DKK1--6892
WNT8A--7061
SMAD2--7224
DUSP2--7903
WNT9B--8495
GDF3--19473
MIXL1--9542
HNF1B--19562
ARC0.2519982
PAX9--110534
GATA4--111137
EOMES--11394
GATA6--113349
WNT9A--14123
TGFB10.25114736
POU5F1--21422
WNT4--21840
KIF16B--22566
LAMC1--24046

Network

GO:0007492

Network
Enrichment
NameDescriptionExternal IDs
SOX2SRY (sex determining region Y)-box 2 Entrez:6657  HGNC: 11195  HPRD: 08921  Ensembl: ENSG00000181449 
PTHLHparathyroid hormone-like hormone Entrez:5744  HPRD: 01348  Ensembl: ENSG00000087494  HGNC: 9607 
DUSP5dual specificity phosphatase 5 Entrez:1847  HGNC: 3071  HPRD: 04349  Ensembl: ENSG00000138166 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
FOXA2forkhead box A2 Entrez:3170  HGNC: 5022  Ensembl: ENSG00000125798  HPRD: 02618 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX2SRY (sex determining region Y)-box 2
PTHLHparathyroid hormone-like hormone
DUSP5dual specificity phosphatase 5
SMAD3SMAD family member 3
FOXA2forkhead box A2
Query geneGeneGene descriptionEdge score
SOX2SOX2SRY (sex determining region Y)-box 2
PTHLHPTHLHparathyroid hormone-like hormone
DUSP5DUSP5dual specificity phosphatase 5
SMAD3SMAD3SMAD family member 3
FOXA2FOXA2forkhead box A2

Troyanskaya Laboratory - Princeton University