ASD

GO:0007416 synapse assembly (34)

GeneInput weightStandardRank
NRCAM0.25149
CDH2--130
DNM3--198
CACNA1A--1231
NLGN10.251265
POU4F1--292
MAP1B--300
DRD10.251662
SPOCK2--901
ACHE--1266
LRP4--1290
PCDHB11--1630
DNER--1640
APP--1991
GLRA2--1994
DRD20.2512071
PCDHB6--2113
PCDHB4--2265
NLGN4Y0.2512355
PCDHB3--2462
NLGN4X1.012551
PCDHB10--2762
PCDHB16--3090
PCDHB9--3226
NLGN31.013428
PCDHB13--3817
PCDHB14--4100
PCDHB5--4689
AGRN0.2515611
PCDHB2--6083
NLGN2--6159
GJA10--8190
CDH1--123441
GNPAT--124183

Network

GO:0007416

Network
Enrichment
NameDescriptionExternal IDs
NRCAMneuronal cell adhesion molecule Entrez:4897  Ensembl: ENSG00000091129  HGNC: 7994  HPRD: 07207 
CDH2cadherin 2, type 1, N-cadherin (neuronal) Entrez:1000  Ensembl: ENSG00000170558  HGNC: 1759  HPRD: 00226 
DNM3dynamin 3 Entrez:26052  HGNC: 29125  Ensembl: ENSG00000197959  HPRD: 13241 
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit Entrez:773  HPRD: 03004  HGNC: 1388  Ensembl: ENSG00000141837 
NLGN1neuroligin 1 Entrez:22871  HGNC: 14291  HPRD: 07195  Ensembl: ENSG00000169760 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NRCAMneuronal cell adhesion molecule
CDH2cadherin 2, type 1, N-cadherin (neuronal)
DNM3dynamin 3
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
NLGN1neuroligin 1
Query geneGeneGene descriptionEdge score
NRCAMNRCAMneuronal cell adhesion molecule
CDH2CDH2cadherin 2, type 1, N-cadherin (neuronal)
DNM3DNM3dynamin 3
CACNA1ACACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
NLGN1NLGN1neuroligin 1

Troyanskaya Laboratory - Princeton University