ASD

GO:0010962 regulation of glucan biosynthetic process (21)

GeneInput weightStandardRank
PPP1CA--67
AKT10.251303
IRS1--11052
IRS2--11607
PPP1CB--1804
IGF10.2511993
GRB10--2023
GCK--12874
AKT2--13025
DYRK2--3180
PTH--5481
ENPP1--15674
SORBS1--6543
C1QTNF2--7354
INSR--110986
PPP1R3C--11393
PPP1R3D--14391
MTOR--15435
INS--119021
PPP1R3E--20812
IGF20.25123391

Network

GO:0010962

Network
Enrichment
NameDescriptionExternal IDs
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme Entrez:5499  Ensembl: ENSG00000172531  HPRD: 15942  HGNC: 9281 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
IRS1insulin receptor substrate 1 Entrez:3667  HPRD: 00943  HGNC: 6125 
IRS2insulin receptor substrate 2 Entrez:8660  HPRD: 02878  HGNC: 6126  Ensembl: ENSG00000185950 
PPP1CBprotein phosphatase 1, catalytic subunit, beta isozyme Entrez:5500  Ensembl: ENSG00000213639  HPRD: 11792  HGNC: 9282 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme
AKT1v-akt murine thymoma viral oncogene homolog 1
IRS1insulin receptor substrate 1
IRS2insulin receptor substrate 2
PPP1CBprotein phosphatase 1, catalytic subunit, beta isozyme
Query geneGeneGene descriptionEdge score
PPP1CAPPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1
IRS1IRS1insulin receptor substrate 1
IRS2IRS2insulin receptor substrate 2
PPP1CBPPP1CBprotein phosphatase 1, catalytic subunit, beta isozyme

Troyanskaya Laboratory - Princeton University