ASD

GO:0050686 negative regulation of mRNA processing (9)

GeneInput weightStandardRank
PTBP1--583
SRSF9--797
SRSF10--2264
SRSF12--2655
SRSF7--3630
BARD1--14151
SRSF4--4276
SRSF6--10440
U2AF2--17548

Network

GO:0050686

Network
Enrichment
NameDescriptionExternal IDs
PTBP1polypyrimidine tract binding protein 1 Entrez:5725  HGNC: 9583  Ensembl: ENSG00000011304  HPRD: 02823 
SRSF9serine/arginine-rich splicing factor 9 Entrez:8683  HPRD: 09053  Ensembl: ENSG00000111786  HGNC: 10791 
SRSF10serine/arginine-rich splicing factor 10 Entrez:10772  HGNC: 16713  HPRD: 05562  Ensembl: ENSG00000188529 
SRSF12serine/arginine-rich splicing factor 12 Entrez:135295  Ensembl: ENSG00000154548  HPRD: 11605  HGNC: 21220 
SRSF7serine/arginine-rich splicing factor 7 Entrez:6432  HGNC: 10789  Ensembl: ENSG00000115875  HPRD: 08991 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PTBP1polypyrimidine tract binding protein 1
SRSF9serine/arginine-rich splicing factor 9
SRSF10serine/arginine-rich splicing factor 10
SRSF12serine/arginine-rich splicing factor 12
SRSF7serine/arginine-rich splicing factor 7
Query geneGeneGene descriptionEdge score
PTBP1PTBP1polypyrimidine tract binding protein 1
SRSF9SRSF9serine/arginine-rich splicing factor 9
SRSF10SRSF10serine/arginine-rich splicing factor 10
SRSF12SRSF12serine/arginine-rich splicing factor 12
SRSF7SRSF7serine/arginine-rich splicing factor 7

Troyanskaya Laboratory - Princeton University