ASD

GO:0048010 vascular endothelial growth factor receptor signaling pathway (21)

GeneInput weightStandardRank
PDGFRA--1233
PRKD1--619
BMPR2--1964
NRP20.2511360
NRP1--1961
FLT10.2512278
MAPKAPK2--3441
KDR0.2513769
FLT3--13966
VEGFA0.2514691
MAPK14--4729
FIGF--5086
VEGFC--5203
PRKD2--5637
PGF--7841
FOXC2--8308
PDGFC--8686
FLT4--111694
FOXS1--15328
VEGFB--20069
FOXC1--122868

Network

GO:0048010

Network
Enrichment
NameDescriptionExternal IDs
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide Entrez:5156  Ensembl: ENSG00000134853  HPRD: 01429  HGNC: 8803 
PRKD1protein kinase D1 Entrez:5587  Ensembl: ENSG00000184304  HPRD: 05668  HGNC: 9407 
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) Entrez:659  Ensembl: ENSG00000204217  HPRD: 02880  HGNC: 1078 
NRP2neuropilin 2 Entrez:8828  HGNC: 8005  Ensembl: ENSG00000118257  HPRD: 03643 
NRP1neuropilin 1 Entrez:8829  HGNC: 8004  Ensembl: ENSG00000099250  HPRD: 03642 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide
PRKD1protein kinase D1
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
NRP2neuropilin 2
NRP1neuropilin 1
Query geneGeneGene descriptionEdge score
PDGFRAPDGFRAplatelet-derived growth factor receptor, alpha polypeptide
PRKD1PRKD1protein kinase D1
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
NRP2NRP2neuropilin 2
NRP1NRP1neuropilin 1

Troyanskaya Laboratory - Princeton University