ASD

GO:0007346 regulation of mitotic cell cycle (267)

GeneInput weightStandardRank
PSMA1--42
PSMB3--79
PSMA4--95
PSMD14--120
PSMD8--144
PAFAH1B10.251208
PSMA5--219
PSMB1--318
PSMA3--373
PSMC4--380
MYO160.251386
TOP2B--389
PSMC6--405
FOXG1--483
APC0.251528
PSMB7--554
PSMB4--562
SOX4--581
PSMD2--595
KIAA2022--629
PPP2R5C--681
PSMB6--696
DGKZ--725
SMARCA4--751
PSMA7--782
PSMC3--794
PSMC5--831
PSMD1--867
PSMD6--884
PSMC1--904
PSMD3--909
PSMD11--943
PSMC2--952
PKIA--959
PROX1--962
BMP7--987
PSMD13--994
WNT10B--1030
APBB2--1049
CDKN1B--1067
CDC42--1083
PTCH1--11149
PSMD4--1166
USP22--1375
RPRM--1426
PSMA6--1492
EDN3--11522
SMAD3--1541
CDC123--1560
TGFA--1563
PSME4--1576
BUB3--1593
FGFR3--11648
PSMA2--1693
APP--1991
IGF10.2511993
PRCC--12010
PSMD10--2012
EIF4E0.2512043
TAL1--2070
SMAD6--2079
PSMD12--2120
PTEN1.012260
FOXA1--2277
PSMD7--2386
APBB1--2444
BRD4--2590
PPP1R9B--2609
NAE1--2658
UBE2L3--2735
DRD30.2512757
RPS6KB1--2773
NKX3-1--2779
CDK13--2792
GML--2793
CHMP1A--2805
USP2--3058
USP44--3386
RB1--13450
NEUROG10.2513515
HOXA13--3602
TERF1--3607
MET1.013618
STAT5B--3888
BCL6--3994
MAD1L1--14183
L3MBTL1--4357
FGF10--14373
BRD7--4450
MAD2L1BP--4513
IL1A--4552
CDKN1A--4620
NEK6--5026
CYP1A10.2515095
PTPN3--5124
MAEA--5169
BMP4--15180
TRRAP--5259
CCND1--15288
CCNB3--5337
MDM2--5588
UBC--5781
CD28--5834
DUSP3--5845
CYLD--15851
GAS1--5960
TMEM8B--6047
ANLN--6172
IL1B--16220
DYNC1LI1--6311
TFAP4--6483
UBE2E1--6513
PCBP4--6619
TPR--7012
PSME2--7488
PSMB9--7654
PSMB2--7801
BTG3--7975
PSMG2--7987
PSMA8--8114
PIN1--8222
EREG--8504
SH2B1--8828
EGF0.2518839
ANAPC2--8902
CDC23--9012
AFAP1L2--9020
NPM2--9156
PDXP--9557
EDN1--9566
CDKN2A--19650
ASNS--9679
DCUN1D3--9959
MTBP--10170
FOXO4--10242
CDK10--10264
DLG1--10557
ATM--110590
TRIM35--10749
INSR--110986
ANAPC10--11143
PEBP1--11226
MAD2L2--11317
PIM3--11365
UBD--11424
EPGN--11496
PSME1--11612
RFWD2--12054
E4F1--12260
HNF4A--112281
PSMB8--12378
RBM38--12396
PDGFB--12484
HRAS0.25112845
SIK1--13156
USP47--13183
E2F1--13572
ANAPC11--13665
PSMD9--13761
PHIP--13849
WNT9A--14123
USP17L2--14209
BID--14222
PSMB11--14440
CDK11A--14473
PSMB10--14502
PRKCQ--14566
AURKAIP1--14704
PLK5--14706
TGFB10.25114736
CDC27--14913
CDKN2B--15696
DYNLT3--15805
TP73--15964
ZNF655--16830
LRP5--116985
PSME3--17451
EIF4EBP1--17707
PSMD5--18391
INS--119021
AATF--19262
STAT5A--19316
HDAC3--19605
TNF0.25119823
PRMT2--20303
THAP1--20677
ILKAP--20790
PDGFRB--21054
CDC26--21067
SPHK1--21548
SIRT2--21600
ASUN--21722
HUS1--21730
NBN--121778
SBDS--21855
TP530.25121968
FBXO31--22074
RANBP1--22188
UBB--22223
CDK11B--22225
CCNG1--22384
CLSPN--22424
CRLF3--22462
CHFR--22695
MAD2L1--22813
TICRR--22831
FOXC1--122868
RPS27A--22920
INO80--22938
PSMF1--22952
TRIAP1--23071
IGF20.25123391
BUB1--23506
UBE2D1--23789
CAV2--23834
PTPN6--23968
CDK1--24001
CDK2--24011
TP63--124113
UBA52--24116
TOP2A--24163
CDC25C--24184
RFWD3--24220
POLD1--24251
SCRIB--24455
PSMB5--24489
ZWINT--24503
RAD17--24604
CCNB1--24648
PSRC1--24661
GTSE1--24676
NUSAP1--24754
BRCA2--124829
RPS27L--24874
ANAPC7--24876
CDC20--24914
ANAPC5--24931
ZW10--24959
CUL4A--25107
NME6--25149
CDT1--25175
ANAPC4--25215
PML--25248
UBE2C--25279
KIF20B--25283
ESPL1--25382
CCNB2--25403
CDC16--25415
RCC1--25428
FBXO5--25430
PCID2--25435
BORA--25436
KNTC1--25464
BIRC5--25475
NEK2--25507
ANAPC1--25548
ZWILCH--25571
CCNA2--25594
CENPF--25617
TPX2--25619
PRMT5--25630
TTK--25644
PKMYT1--25675
PLK1--25689
DLGAP5--25692
CDC6--25778
BUB1B--125795

Network

GO:0007346

Network
Enrichment
NameDescriptionExternal IDs
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1 Entrez:5682  Ensembl: ENSG00000129084  HPRD: 04170  HGNC: 9530 
PSMB3proteasome (prosome, macropain) subunit, beta type, 3 Entrez:5691  HPRD: 03709  Ensembl: ENSG00000108294  HGNC: 9540 
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4 Entrez:5685  Ensembl: ENSG00000041357  HPRD: 10168  HGNC: 9533 
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 Entrez:10213  HGNC: 16889  Ensembl: ENSG00000115233  HPRD: 06208 
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 Entrez:5714  Ensembl: ENSG00000099341  HPRD: 10171  HGNC: 9566 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMB3proteasome (prosome, macropain) subunit, beta type, 3
PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
Query geneGeneGene descriptionEdge score
PSMA1PSMA1proteasome (prosome, macropain) subunit, alpha type, 1
PSMB3PSMB3proteasome (prosome, macropain) subunit, beta type, 3
PSMA4PSMA4proteasome (prosome, macropain) subunit, alpha type, 4
PSMD14PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
PSMD8PSMD8proteasome (prosome, macropain) 26S subunit, non-ATPase, 8

Troyanskaya Laboratory - Princeton University