ASD

GO:0043949 regulation of cAMP-mediated signaling (9)

GeneInput weightStandardRank
PEX5L--531
CDC34--1858
MGRN1--2411
UBE2B--2708
PDE3B--3088
CRHR2--3445
GIP--3965
RASD2--5271
PEBP1--11226

Network

GO:0043949

Network
Enrichment
NameDescriptionExternal IDs
PEX5Lperoxisomal biogenesis factor 5-like Entrez:51555  HGNC: 30024  HPRD: 11425  Ensembl: ENSG00000114757 
CDC34cell division cycle 34 Entrez:997  HGNC: 1734  Ensembl: ENSG00000099804  HPRD: 00306 
MGRN1mahogunin ring finger 1, E3 ubiquitin protein ligase Entrez:23295  HPRD: 07397  HGNC: 20254  Ensembl: ENSG00000102858 
UBE2Bubiquitin-conjugating enzyme E2B Entrez:7320  Ensembl: ENSG00000119048  HPRD: 01533  HGNC: 12473 
PDE3Bphosphodiesterase 3B, cGMP-inhibited Entrez:5140  HGNC: 8779  Ensembl: ENSG00000152270  HPRD: 03626 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PEX5Lperoxisomal biogenesis factor 5-like
CDC34cell division cycle 34
MGRN1mahogunin ring finger 1, E3 ubiquitin protein ligase
UBE2Bubiquitin-conjugating enzyme E2B
PDE3Bphosphodiesterase 3B, cGMP-inhibited
Query geneGeneGene descriptionEdge score
PEX5LPEX5Lperoxisomal biogenesis factor 5-like
CDC34CDC34cell division cycle 34
MGRN1MGRN1mahogunin ring finger 1, E3 ubiquitin protein ligase
UBE2BUBE2Bubiquitin-conjugating enzyme E2B
PDE3BPDE3Bphosphodiesterase 3B, cGMP-inhibited

Troyanskaya Laboratory - Princeton University