ASD

GO:0032410 negative regulation of transporter activity (22)

GeneInput weightStandardRank
CALM3--195
SNCA--1401
IL1RAPL10.251519
CALM1--708
ADRA2A0.2511556
DRD20.2512071
CALM2--2360
NCS1--2387
DRD30.2512757
OPRD10.2513266
NDFIP1--4331
STIM2--5530
GNAI2--6384
DRD40.2517058
RHOC--9929
INSR--110986
NDFIP2--11428
WWP2--12103
EPO--12314
APOA2--12739
SLC9A3R1--21807
ADRB20.25122718

Network

GO:0032410

Network
Enrichment
NameDescriptionExternal IDs
CALM3calmodulin 3 (phosphorylase kinase, delta) Entrez:808  HPRD: 00243  Ensembl: ENSG00000160014  HGNC: 1449 
SNCAsynuclein, alpha (non A4 component of amyloid precursor) Entrez:6622  HPRD: 01227  HGNC: 11138  Ensembl: ENSG00000145335 
IL1RAPL1interleukin 1 receptor accessory protein-like 1 Entrez:11141  HPRD: 02193  HGNC: 5996 
CALM1calmodulin 1 (phosphorylase kinase, delta) Entrez:801  HPRD: 00241  HGNC: 1442  Ensembl: ENSG00000198668 
ADRA2Aadrenoceptor alpha 2A Entrez:150  HGNC: 281  HPRD: 00078  Ensembl: ENSG00000150594 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CALM3calmodulin 3 (phosphorylase kinase, delta)
SNCAsynuclein, alpha (non A4 component of amyloid precursor)
IL1RAPL1interleukin 1 receptor accessory protein-like 1
CALM1calmodulin 1 (phosphorylase kinase, delta)
ADRA2Aadrenoceptor alpha 2A
Query geneGeneGene descriptionEdge score
CALM3CALM3calmodulin 3 (phosphorylase kinase, delta)
SNCASNCAsynuclein, alpha (non A4 component of amyloid precursor)
IL1RAPL1IL1RAPL1interleukin 1 receptor accessory protein-like 1
CALM1CALM1calmodulin 1 (phosphorylase kinase, delta)
ADRA2AADRA2Aadrenoceptor alpha 2A

Troyanskaya Laboratory - Princeton University