ASD

GO:0009948 anterior/posterior axis specification (34)

GeneInput weightStandardRank
PCSK6--731
LRP6--778
PGAP1--865
OTX2--11295
FOXA2--1835
LHX1--1926
NODAL--12184
T--2584
SRF--2700
WNT5A--2870
SMAD4--2927
EPB41L5--3311
HOXB6--3623
TBX3--3843
SKI--4231
WNT3--4799
GPC3--15153
BMP4--15180
CER1--5192
CTNNB10.2516229
TDRD5--6427
HOXD8--6575
TDGF1--6833
RIPPLY2--7060
WNT8A--7061
RIPPLY1--8488
RNF2--8552
GDF3--19473
FRS2--12610
TCF7L1--13850
LDB1--14274
WLS--16366
FZD5--21891
PLD6--22708

Network

GO:0009948

Network
Enrichment
NameDescriptionExternal IDs
PCSK6proprotein convertase subtilisin/kexin type 6 Entrez:5046  HPRD: 01329  HGNC: 8569  Ensembl: ENSG00000140479 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
PGAP1post-GPI attachment to proteins 1 Entrez:80055  HGNC: 25712  HPRD: 10147 
OTX2orthodenticle homeobox 2 Entrez:5015  HGNC: 8522  HPRD: 07190  Ensembl: ENSG00000165588 
FOXA2forkhead box A2 Entrez:3170  HGNC: 5022  Ensembl: ENSG00000125798  HPRD: 02618 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PCSK6proprotein convertase subtilisin/kexin type 6
LRP6low density lipoprotein receptor-related protein 6
PGAP1post-GPI attachment to proteins 1
OTX2orthodenticle homeobox 2
FOXA2forkhead box A2
Query geneGeneGene descriptionEdge score
PCSK6PCSK6proprotein convertase subtilisin/kexin type 6
LRP6LRP6low density lipoprotein receptor-related protein 6
PGAP1PGAP1post-GPI attachment to proteins 1
OTX2OTX2orthodenticle homeobox 2
FOXA2FOXA2forkhead box A2

Troyanskaya Laboratory - Princeton University