ASD

GO:0070169 positive regulation of biomineral tissue development (28)

GeneInput weightStandardRank
BMPR2--1964
BMP7--987
WNT10B--1030
FBN2--1425
SMAD3--1541
ACVR2A--1768
BMPR1A--2059
BMPR1B--12397
TFAP2A--12460
WNT6--2891
AMELX--12925
ACVR2B--13179
BMP6--3242
KL--3641
BMP2--13686
BMP4--15180
TGFB3--15321
OSR1--6192
P2RX7--6517
CD276--9565
ACVR1--111780
PKDCC--13669
TGFB10.25114736
PPARGC1B--116411
PLA2G4A--18503
OSR2--18904
WNT4--21840
ADRB20.25122718

Network

GO:0070169

Network
Enrichment
NameDescriptionExternal IDs
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) Entrez:659  Ensembl: ENSG00000204217  HPRD: 02880  HGNC: 1078 
BMP7bone morphogenetic protein 7 Entrez:655  Ensembl: ENSG00000101144  HGNC: 1074  HPRD: 00212 
WNT10Bwingless-type MMTV integration site family, member 10B Entrez:7480  Ensembl: ENSG00000169884  HGNC: 12775  HPRD: 03548 
FBN2fibrillin 2 Entrez:2201  Ensembl: ENSG00000138829  HGNC: 3604  HPRD: 00416 
SMAD3SMAD family member 3 Entrez:4088  HPRD: 04380  HGNC: 6769  Ensembl: ENSG00000166949 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
BMP7bone morphogenetic protein 7
WNT10Bwingless-type MMTV integration site family, member 10B
FBN2fibrillin 2
SMAD3SMAD family member 3
Query geneGeneGene descriptionEdge score
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
BMP7BMP7bone morphogenetic protein 7
WNT10BWNT10Bwingless-type MMTV integration site family, member 10B
FBN2FBN2fibrillin 2
SMAD3SMAD3SMAD family member 3

Troyanskaya Laboratory - Princeton University